Novel technologies are playing an important role in the development of crop and livestock farming and have the potential to be the key drivers of sustainable intensification of agricultural systems. In particular, new sensors are now available with reduced dimensions, reduced costs, and increased performances, which can be implemented and integrated in production systems, providing more data and eventually an increase in information. It is of great importance to support the digital transformation, precision agriculture, and smart farming, and to eventually allow a revolution in the way food is produced. In order to exploit these results, authoritative studies from the research world are still needed to support the development and implementation of new solutions and best practices. This Special Issue is aimed at bringing together recent developments related to novel sensors and their proved or potential applications in agriculture.