Serum 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D are decreased in dogs with sinonasal aspergillosis.

• Tác giả: Frédéric Billen, Etienne Cavalier, Cécile Clercx, Jared A Jaffey, Caroline Le Goff, Dominique Peeters, Stéphanie Peeters, Nina F Rodrigues, Arnaud Snoeck
• Ngôn ngữ: eng
• Ký hiệu phân loại: 002.074 Museums, collections, exhibits
• Thông tin xuất bản: England : Veterinary journal (London, England : 1997) , 2025
• Bộ sưu tập: NCBI
• ID: 225595

Tóm tắt

Canine sinonasal aspergillosis (SNA) is a poorly understood disease and remains a challenge to treat. Hypovitaminosis D is associated with many infectious diseases in humans and Vitamin D (VitD) deficiency in experimental mice decreases resistance to Aspergillus fumigatus. The objective of this study was to determine whether dogs with SNA have different VitD metabolite concentrations compared to healthy dogs (HD) and dogs with other nasal conditions and if those concentrations change after cure for SNA dogs. Twenty-two dogs with SNA, 12 HD, 9 dogs with lymphoplasmacytic rhinitis (LPR) and 10 dogs with nasal neoplasia (NN) were included. Serum 25-hydroxyvitamin D