Stressed microglia turn to the dark side in Alzheimer's disease.

• Tác giả: Gilbert Di Paolo, Joseph W Lewcock
• Ngôn ngữ: eng
• Ký hiệu phân loại: 636.0885 Animal husbandry
• Thông tin xuất bản: United States : Neuron , 2025
• Bộ sưu tập: NCBI
• ID: 226001

Tóm tắt

A microglia subpopulation termed "dark microglia" has been associated with aging and neurodegeneration, although its role has remained elusive. New research from Flury et al. in this issue of Neuron shows that dark microglia drive neurodegeneration via secretion of toxic lipids.