Peptide-conjugated alginate fiber: A skeletal muscle regenerative scaffold.

• Tác giả: Jianwu Dai, Lin Li, Yajun Li, Liyang Shi, Jianping Tang, Tong Wu, Yueren Wu, Can Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 976.3 *Louisiana
• Thông tin xuất bản: England : Carbohydrate polymers , 2025
• Bộ sưu tập: NCBI
• ID: 226530

Tóm tắt

Biopolymeric fibers have garnered significant attention in biomedical applications due to their ability to promote tissue regeneration through aligned microstructures. Alginate (Alg) is commonly used to prepare wet-spun fibers through ionic interactions. However, ion-crosslinked Alg fibers present limitations in tissue regeneration due to their rapid degradation under physiological conditions and the absence of binding sites for bioactive molecules. In this study, oxidized methacrylated alginate (OMA) derivatives were synthesized to create Alg fibers crosslinked by both Ca