O-GlcNAcylation and Cancer

• Tác giả: Ikram El Yazidi-Belkoura, Tony Lefebvre
• Ngôn ngữ: eng
• ISBN-13: 978-3036530826
• Thông tin xuất bản: Basel : MDPI - Multidisciplinary Digital Publishing Institute, 2022
• Mô tả vật lý: 1 electronic resource (112 p.)
• Bộ sưu tập: Tài liệu truy cập mở
• ID: 228336
• Chủ đề: 1. Research & information: general

Tóm tắt

This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed.