Discovery of Novel and Highly Potent Dual PD-L1/Histone Deacetylase 6 Inhibitors with Favorable Pharmacokinetics for Cancer Immunotherapy.

• Tác giả: Jianjun Chen, Binbin Cheng, Haiqi He, Ying Hu, Zhihao Hu, Feng Jiang, Shuqing Li, Hailiu Liang, Ting Liu, Benyan Lu, Wanyi Pan, Xiaopeng Peng, Zetao Qi, Chengpeng Tao, Congcong Xu
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Journal of medicinal chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 229380

Tóm tắt

A series of novel PD-L1/HDAC6 dual inhibitors were designed and synthesized, and compound