We characterise the clinical parameters of patients referred for isolated neutropenia who were found to express the Duffy null phenotype and subsequent diagnosis of Duffy null associated neutrophil count (DANC). This is a single-centre, retrospective review of adult patients (18 years and over) who were referred to a tertiary hospital for further investigation of isolated neutropenia between June 2023 and February 2024. Patient demographics, co-morbidities, ethnicity, medications, laboratory results and final diagnosis were obtained from electronic database and chart reviews. Data were collated and analysed using descriptive statistics. A total of 34 patients (35.3% male) were identified, with a median age of 43 years (IQR 31, 61). The median absolute neutrophil count was 1.42×10