Heterogeneous Fe-N-C Cocatalyst for Hydroquinone Oxidation Enables Aerobic Oxidation of Primary Alcohols to Aldehydes.

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Tác giả: Hansjörg Grützmacher, Md Asmaul Hoque, Jesse J Martinez, Vittorio Sacchetti, Clara Schweinzer, Shannon S Stahl, Friederike Tewes

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Germany : Angewandte Chemie (International ed. in English) , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 231066

Benzoquinone (BQ) is commonly used as a cocatalyst in multi-component catalyst systems for aerobic oxidation of organic molecules. Such methods often proceed by a redox cascade in which a secondary catalyst supports aerobic oxidation of hydroquinone (HQ) to BQ. The present study shows that a commercially available non-precious metal heterogeneous catalyst, PAJ-Fe-N-C, is much more efficient than established homogeneous catalysts for aerobic oxidation of HQ to BQ, and this improved reactivity is crucial to support aerobic oxidation of primary alcohols to aldehydes with the homogeneous iridium catalyst, [Ir(trop2DAD]OTf (trop2DAD = N,N-bis(5-H-dibenzo[a,d]cyclo-heptene-5-yl)-1,4-diazabuta-1,3-diene). The combination of this heterogeneous/homogeneous catalyst system operates with Ir catalyst loadings as low as 0.05 mol % and turnover frequencies ≥350 h-1.
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