Virulence Factors and Antibiotic Resistance of Enterobacterales

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Tác giả: Dobroslava Bujňáková, Ivana Ćirković, Nikola Puvača

Ngôn ngữ: eng

ISBN-13: 978-3036527802

Ký hiệu phân loại:

Thông tin xuất bản: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022

Mô tả vật lý: 1 electronic resource (132 p.)

Bộ sưu tập: Tài liệu truy cập mở

ID: 231786

 This book compiles research on Enterobacterales characterization concerning the presence of genes associated with virulence (adhesins
  surface cellulose structures and curli
  siderophores, e.g., enterobactin, aerobactin, and yersiniabactin
  protectines
  invasins or toxins), and, furthermore, bacterial-biofilm-associated phenotypes. Although not directly involved in pathogenicity, the acquisition of multiple antibiotic resistances strongly supports the success of opportunistic Enterobacterales pathogens in invasion, survival, and spread and markedly complicates the treatment of infections. Not only pathogens, but also commensal bacteria, considered harmless and part of the normal microbiota, are exposed to selection pressure and can be a reservoir of mobile genetic elements carrying antibiotic resistance genes. Therefore, the occurrence of drug-resistant bacteria within a commensal population and the possibility to exchange genetic material through horizontal gene transfer may represent a major health concern.
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