Snapshots of acyl carrier protein shuttling in human fatty acid synthase.

• Tác giả: Pedro Costa-Pinheiro, Lauren Gardner, Sarah M Gardner, Ronen Marmorstein, Laura V Pinheiro, Julio Ramirez-Solis, Kollin Schultz, Kathryn E Wellen
• Ngôn ngữ: eng
• Ký hiệu phân loại: 280.4 Protestant churches and Protestantism
• Thông tin xuất bản: England : Nature , 2025
• Bộ sưu tập: NCBI
• ID: 233075

Tóm tắt

The mammalian fatty acid synthase (FASN) enzyme is a dynamic multienzyme that belongs to the megasynthase family. In mammals, a single gene encodes six catalytically active domains and a flexibly tethered acyl carrier protein (ACP) domain that shuttles intermediates between active sites for fatty acid biosynthesis