Children's sun safety habits have been studied globally, but there is a significant research gap in the western region of Saudi Arabia. This study aimed to assess caregivers' knowledge and attitudes about sun safety for children and adolescents in the Western region of Saudi Arabia. We conducted a cross-sectional study through a validated online questionnaire directed to caregivers living in the Western region of Saudi Arabia. Using 50% and 75% as cutoff thresholds, individuals were divided into three knowledge levels: low (scores from 15 to 44), average (from 45 to 59), and high (from 60 to 75). The study included 940 caregivers (53% were mothers). The majority of caregivers (73%) demonstrated an average level of knowledge about sun protection, with notable misconceptions such as the belief that sun protection is unnecessary in winter. Most of the participants could accurately identify health risks associated with excessive sun exposure such as the risk of skin cancer. Binary logistic regression analysis revealed that having a child aged 1 year or younger was an independent predictor of higher knowledge levels regarding sun exposure and protection (OR = 1.27
95% CI: 1.01-1.6). Sun protection practices were inconsistent
28.7% of caregivers never used sunscreen themselves, 34.9% never used them for their children and 23% used it exclusively in the summer months. In conclusion, while most participants exhibited average knowledge about sunlight exposure and protection, only 23.1% of caregivers applied sunscreen regularly on their children.