DNA Framework-Enabled Ocular Barrier Penetration for Microinvasive Antiangiogenic Therapy.

• Tác giả: Qi Chen, Chunhai Fan, Chunhong Li, Fan Li, Qian Li, Lin Liu, Yanhan Liu, Xiuhai Mao, Lu Song, Ruobing Wang, Tianqin Wang, Jiayang Xiang, Wenjuan Xiao, Qiuxue Yi, Yuelu Zhang, Xiaolei Zuo
• Ngôn ngữ: eng
• Ký hiệu phân loại: 612.042 Work
• Thông tin xuất bản: United States : Journal of the American Chemical Society , 2025
• Bộ sưu tập: NCBI
• ID: 234703

Tóm tắt

Therapeutic aptamers targeting vascular endothelial growth factor A (VEGFA) have advanced the development of antiangiogenic drugs for treating choroidal neovascularization (CNV) diseases. However, despite FDA approval for use in neovascular age-related macular degeneration (nAMD), the effective