Intracellular Photocatalytic NADH/NAD(P)H Oxidation for Cancer Drug Development.

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Tác giả: Samya Banerjee, Rajesh Kushwaha, Apurba Mandal, Arif Ali Mandal, Ashish Kumar Yadav

Ngôn ngữ: eng

Ký hiệu phân loại: 363.3498 Other aspects of public safety

Thông tin xuất bản: United States : Journal of the American Chemical Society , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 236272

Photocatalytic cancer therapy (PCT) has emerged as a cutting-edge anticancer mechanism of action, harnessing light energy to mediate the catalytic oxidation of intracellular substrates. PCT is of significant current importance due to its potential to address the limitations of conventional chemotherapy, particularly drug resistance and side effects. This approach offers a noninvasive, targeted cancer treatment option by utilizing metal-based photocatalysts to induce redox and metabolic disorders within cancer cells. The photocatalysts disrupt the cancer cell metabolism by converting NADH/NAD(P)H to NAD
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