Although it is true that the coronavirus disease 2019 (COVID-19) situation has improved significantly around the world, especially after the implementation of mass vaccination campaigns, there is still a lack of consensus both in the literature and among health authorities and other stakeholders about the current epidemiological situation. This, in turn, has been intensified after the World Health Organization declared the end of the public health emergency of international concern related to COVID-19. In this context, worrying questions have arisen, including a rampant dissemination of scientific misinformation coupled with increased resistance to the implementation and/or revocation of appropriate public health measures. In response to these challenges and hoping to contribute to their mitigation, this article addresses current aspects about the epidemiological situation of COVID-19, discusses long COVID and its controversies, the intensification of scientific misinformation as well as considerations on related health surveillance, and recommendations for improving the existing situation.