INTRODUCTION: In mammals, Paneth cells, located in the crypts of the small intestine, produceantimicrobial peptides that serve to keep the intestinal microbiome under control. a-Defensins are the primary antimicrobial peptides produced by these cells. METHODS: We used 148 publicly available bulk RNA-seq samples on purified PCs, proteomics on enriched purified PC proteins and RESULTS: We identified 28 expressed CONCLUSION: We show the existence of chimeric