A Cross-sectional Study for the Correlation of Vitamin D Level and Severity of Early Rheumatoid Arthritis.

• Tác giả: Insha Aleena, Sudipto Chakraborty, Shreya Choudhury, Pradip Dey, Sakshi Puri, Siktha Purkait, Mohidur Rahaman, Rajeswar Samanta, Dhiman Sen, Swagatam Sengupta, Parineeta Singhal
• Ngôn ngữ: eng
• Thông tin xuất bản: India : Annals of African medicine , 2025
• Bộ sưu tập: NCBI
• ID: 239458

Tóm tắt

 BACKGROUND: Rheumatoid arthritis (RA) is a chronic inflammatory multisystemic disorder that can cause significant deformity and disability. Vitamin D has a role in Th1-medicated autoimmune diseases like RA. Furthermore, some observational studies have concluded that Vitamin D supplementation reduces the severity of RA. AIMS: This study aimed to find out any correlation between Vitamin D levels and severity of early RA. SETTINGS AND DESIGN: This study settings and design were a cross-sectional single-center observational study. MATERIALS AND METHODS: This was an observational study. All patients with early RA were screened and evaluated as per protocol. No extra tests were done. STATISTICAL ANALYSIS USED: Pearson's Chi-square test for independence of attributes/Fisher's exact test was used to find the association between the categorical variables as appropriate. RESULTS AND CONCLUSION: We found that all patients of early RA had moderate-tosevere disease activity without any relation with their Vitamin D level (P >
  0.05).