Development of Engineered Microparticles for Investigating Enzymatic Degradation of Proteins and Peptides within Phagosomes.

• Tác giả: Maryam Ayazi, Masahiro Fukuda, Jingjiao Guan, Grace Hammel, Sailesti Joshi, Abigail Kizer, Grace Lin, Yang Liu, Yuan Liu, Yi Ren
• Ngôn ngữ: eng
• Ký hiệu phân loại: 338.9 Economic development and growth
• Thông tin xuất bản: United States : ACS applied materials & interfaces , 2025
• Bộ sưu tập: NCBI
• ID: 243035

Tóm tắt

Phagocytosis involves the engulfment and enzymatic degradation of particulate objects by phagocytes in a compartment called a phagosome. The degradation mechanisms for natural phagocytic objects such as proteins and peptides are not well understood. To explore this, we developed a novel method using microparticles made of proteins and/or peptides and poly(