Đánh giá thực trạng đề kháng kháng sinh của một số vi khuẩn phân lập trong hệ thống Bệnh viện Xuyên Á từ năm 2021-2023=Assessing the situation antibiotic resistance of some bacteria isolated in Xuyen A Hospital system from 2021-2023

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Tác giả: Hoàng Thảo Nguyễn, Minh Tuấn Nguyễn, Ngọc Cẩm Vân Nguyễn, Thị Bông Nguyễn, Duy Thanh Phạm, Thị Thùy Linh Phan, Thị Thu Hà Trần, Trung Việt Võ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.92-100

Bộ sưu tập: Metadata

ID: 243467

Thêm vào giỏ

To identify the commonly isolated bacterial strains and the rate of antibiotic resistance of bacterial strains. Determine the distribution of antibiotic resistance rates of bacterial strains in each hospital in Xuyen A Hospital System. Methods: Using the cross-sectional descriptive method and based on bacterial isolation data and antibiograms of bacterial strains at the microbiology department of hospitals in Xuyen A Hospital System. Results: There were 7,093 types of clinical samples taken for culture and antibiotic susceptibility testing. Of these, 76.03% were Gram-negative bacteria and 23.97% were Gram-positive bacteria. The leading Gram-negative bacteria were E. coli 27.79%
K. pneumoniae 15.03%
A. baumannii 4.7%
P. aeruginosa 4.46%. The most common Gram-positive bacteria were S. aureus 15.51%. The antibiotic resistance level of Gram-negative bacteria was high to β-lactamase antibiotics combined with β-lactamase inhibitors, 3rd generation Cephalosporins, and Fluoroquinolones. The carbapenem antibiotic resistance level of K. pneumoniae bacteria was from 12-15%. 80% of S. aureus bacteria were resistant to methicillin. Conclusion: The causative agent of infection in patients is usually Gram-negative strains accounting for 76% and Gram-positive accounting for 24%. In particular, the level of resistance to carbapenem antibiotics of K. pneumoniae bacteria was recorded at 12-15%, there are 72% of E. coli resistant to the Fluoroquinolone group and 80% of S. aureus strains were resistant to methicillin.Xác định chủng vi khuẩn thường phân lập được và tỷ lệ đề kháng kháng sinh của các chủng vi khuẩn. Xác định phân bố tỷ lệ kháng kháng sinh của các chủng vi khuẩn trong từng bệnh viện trong HT.BVXA. Phương pháp: Sử dụng phương pháp mô tả cắt ngang và dựa trên số liệu phân lập vi khuẩn và kháng sinh đồ của các chủng vi khuẩn tại khoa vi sinh của các bệnh viện trong HT.BVXA. Kết quả: Có 7.093 loại mẫu bệnh phẩm được lấy nuôi cấy và làm kháng sinh đồ. Trong đó có 76,03% là chủng vi khuẩn Gram âm và 23,97% là chủng vi khuẩn Gram dương. Loại vi khuẩn Gram âm đứng đầu là E. coli 27,79%
K. pneumoniae 15,03%
A. baumannii 4,7%
P. aeruginosa 4,46%. Loại vi khuẩn Gram dương thường gặp là S. aureus 15,51%. Mức độ kháng kháng sinh của các chủng vi khuẩn Gram âm đề kháng cao với kháng sinh nhóm β-lactamase phối hợp với chất ức chế β-lactamase, Cephalosporin thế hệ 3, Fluoroquinolone. Mức độ kháng kháng sinh nhóm carbapenem của các vi khuẩn K. pneumoniae từ 12-15%. 80% vi khuẩn S. aureus kháng với Methicillin. Kết luận: Tác nhân gây nhiễm khuẩn ở bệnh nhân thường là chủng vi khuẩn Gram âm chiếm 76% và Gram dương chiếm 24%. Trong đó, ghi nhận mức độ kháng kháng sinh nhóm Carbapenem của các vi khuẩn K. pneumoniae từ 12-15%, có 72% E. coli kháng với nhóm Fluoroquinolone và có 80% chủng vi khuẩn S. aureus kháng Methicillin.

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