Nghiên cứu thực trạng nhiễm vi khuẩn đa kháng và các giải pháp can thiệp tại thành phố Đà Nẵng=Study on the current situation of multi-resistant bacterial infection and intervention solutions in Da Nang City

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Tác giả: Công Minh Đinh, Hữu Hiếu Hoàng, Vũ Kỳ Nam Lê, Trần Xuân Anh Phạm, Xuân Anh Phạm, Hoàng Thanh Hằng Trần, Thị Khánh Ngọc Trần, Phạm Hoàng Quyên Trương, Thị Thu Hiền Vũ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.11-18

Bộ sưu tập: Metadata

ID: 243545

Thêm vào giỏ

Đánh giá thực trạng nhiễm vi khuẩn đa kháng tại Bệnh viện Đà Nẵng, Bệnh viện Phụ Sản - Nhi Đà Nẵng và Bệnh viện Ung bướu Đà Nẵng và đánh giá hiệu quả của các giải pháp can thiệp hiện tại giảm nhiễm vi khuẩn đa kháng tại Bệnh viện Đà Nẵng. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên tất cả các mẫu kháng sinh đồ tại ba bệnh viện lớn tại Đà Nẵng từ tháng 06/2021 đến tháng 05/2022 (giai đoạn I) và nghiên cứu tiến cứu có can thiệp trên các mẫu kháng sinh đồ tại Bênh viện Đà Nẵng từ tháng 03/2022 đến tháng 10/2023 (giai đoạn II) Kết quả: Tỷ lệ các loại vi khuẩn đa kháng CRE, CRAB, CRP, MRSA, VRE tại thành phố Đà Nẵng trong giai đoạn I lần lượt là 18,3%
69,2%
37,4%
75,9% và 26,4% trong đó tỷ lệ tất cả vi khuẩn đa kháng ngoại trừ MRSA của Bệnh viện Đà Nẵng cao hơn hai bệnh viện khác. Trong giai đoạn II, các biện pháp kiểm soát nhiễm khuẩn đã làm giảm xu hướng tăng tỷ lệ vi khuẩn đa kháng tại Bệnh viện Đà Nẵng với hệ số hồi quy sau can thiệp của CRE, CRAB, CRP, MRSA lần lượt là -0,028
-0,027
-0,009
-0,014, tuy nhiên chỉ có hệ số CRE có ý nghĩa (p = 0,03). Kết luận: Tình trạng đề kháng kháng sinh tại các Bệnh viện Đà Nẵng còn rất cao. Các biện pháp kiểm soát nhiễm khuẩn có thể làm giảm đáng kể tỷ lệ các loại vi khuẩn đa kháng, đặc biệt là vi khuẩn CRE.Evaluate the multidrug-resistant (MDR) bacterial pathogens rates in Danang Hospital, Danang Hospital for Women and Children, Danang Oncology Hospital and evaluate the efficacy of infection control measures in the rate reduction of multidrug resistant bacteria. Methods: A cross-sectional study was conducted in three large hospitals in Danang from June 2021 to May 2022 (Period I) and an interventional prospective study was conducted in Danang Hospital from March 2022 to October 2023 (Period II). Results: The rate of CRE, CRAB, CRP, MRSA, VRE in three large hospitals in Danang were 18.3%, 69.2%, 37.4%, 75.9%, and 26.4%, respectively. The rate of all evaluated multidrug resistant bacteria, except MRSA, were higher in Danang Hospital than two other hospitals. In the Period II, the infection control measures may influence the decrease in multidrug resistant rate with the post-interventional coefficients of interrupted linear regression of CRE, CRAB, CRP, MRSA were -0.028
-0.027
-0.009
-0.014 respectively with corresponding value of CRE was statistically significant (p = 0.03). Conclusion: The multidrug resistance rates in hospitals in Danang were very high. Infection control measures may help to decrease the rate of MDR bacteria, especially CRE.

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