Khảo sát các vi khuẩn gây nhiễm khuẩn tiết niệu tại Bệnh viện Đa khoa tỉnh Ninh Thuận=Survey of bacteria causing urinary infection at Ninh Thuan Province General Hospital

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Tác giả: Huy Thạch Lê, Quốc Thắng Lê, Thị Hoa Lê, Huỳnh Như Ý Nguyễn, Thái Đăng Khoa Nguyễn, Vĩnh Nghi Nguyễn, Vĩnh Châu Võ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.65-73

Bộ sưu tập: Metadata

ID: 243703

Thêm vào giỏ

Nhiễm khuẩn tiết niệu có tỷ lệ tử vong thấp hơn các nhiễm khuẩn khác nhưng là nguy cơ cao dẫn đến nhiễm khuẩn huyết và tăng thời gian, chi phí điều trị. Đối tượng, phương pháp: Mô tả cắt ngang có phân tích. Lấy 249 mẫu nước tiểu nuôi cấy có các chủng vi khuẩn gây nhiễm khuẩn tiết niệu phân lập được tại Bệnh viện đa khoa tỉnh Ninh Thuận từ 01/10/2022 đến 30/9/2023. Kết quả: Tỷ lệ cấy vi khuẩn có trong nước tiểu dương tính là 98.8%
Trong đó, vi khu ẩn Gram âm chiếm 96.4% và vi khuẩn Gram dương chiếm 3.6%. Tổng số chủng Escherichia coli phân lập được chiếm tỷ lệ cao nhất là 62.2%, Klebsiella spp. (19.3%), Proteus spp. (5.6%), Pseudomonas aeruginosa (5.3%), Acinetobacter spp. (3.6%), Enterrococus spp. (2.0%), Staphylococcus aureus (1.2%), Streptococcus spp. (0.4%), Nấm Candida spp. (0.4%). Số lượng vi khuẩn phân lập được chủ yếu ở mức >
= 105 CFU/ml. Escherichia coli đề kháng với Ampicilin (97%), Bactrim (88.3%), Tetracycline (75.4%), Cefuroxime (75%), Ciprofloxacin (65.7%), Cefotaxim (65.5%), Levofloxacin (63.9%), Ceftazidime (60.8%), Ceftriaxone (60.6%), Cefepime (52.8%). Klebsiella spp.: đề kháng Ampicilin (100%), Bactrim (95.8%), Ciprofloxacin (77.8%), Tetracycline (71.1%), Cefuroxime (62.5%), Levofloxacin (60.0%), Ampicilin-Sulbactam (60.0%), Cefotaxim (57.1%), Ceftriaxone (52.6%), Ceftazidime (50.0%). Proteus spp.: đề kháng với Ceftazidime (53.3%), Gentamycin (41.7%), Ciprofloxacin (33.3%), Levofloxacin (33.3%), Cefepime (20%). Enterococcus spp.: đề kháng với Tetracycline (86.7%), Ciprofloxacin (64.3%), Levofloxacin (57.1%). Kết luận: Tình hình kháng kháng sinh của các vi khuẩn gây nhiễm khuẩn tiết niệu ngày càng gia tăng. Vì thế, trong việc điều trị nhiễm trùng tiểu các bác sĩ lâm sàng hiện tại cần chú ý theo đúng các hướng dẫn điều trị để tránh làm gia tăng mức độ kháng thuốc của các vi khuẩn để có thể đạt được kết quả điều trị tối ưu.Urinary tract infections have a lower mortality rate than other infections but pose a high risk of leading to sepsis and increasing treatment time and costs. Methods: Analytical cross-sectional description. Take 249 urine culture samples containing bacterial strains that cause urinary tract infections isolated at Ninh Thuan Provincial General Hospital from October 1, 2022 to September 30, 2023. Results: The rate of positive bacterial cultures in urine is 98.8%
Of these, Gramnegative bacteria account for 96.4% and Grampositive bacteria account for 3.6%. The total number of isolated Escherichia coli strains accounted for the highest proportion of 62.2%, Klebsiella spp. (19.3%), Proteus spp. (5.6%), Pseudomonas aeruginosa (5.3%), Acinetobacter spp. (3.6%), Enterrococus spp. (2.0%), Staphylococcus aureus (1.2%), Streptococcus spp. (0.4%), Candida spp. (0.4%). The number of isolated bacteria was mainly >
= 105 CFU/ml. Escherichia coli resistant to Ampicillin (97%), Bactrim (88.3%), Tetracycline (75.4%), Cefuroxime (75%), Ciprofloxacin (65.7%), Cefotaxim (65.5%), Levofloxacin (63.9%), Ceftazidime (60.8 %), Ceftriaxone (60.6%), Cefepime (52.8%). Klebsiella spp.: resistant to Ampicillin (100%), Bactrim (95.8%), Ciprofloxacin (77.8%), Tetracycline (71.1%), Cefuroxime (62.5%), Levofloxacin (60.0%), Ampicillin-Sulbactam (60.0%), Cefotaxime (57.1%), Ceftriaxone (52.6%), Ceftazidime (50.0%). Proteus spp.: resistant to Ceftazidime (53.3%), Gentamycin (41.7%), Ciprofloxacin (33.3%), Levofloxacin (33.3%), Cefepime (20%). Enterococcus spp.: resistant to Tetracycline (86.7%), Ciprofloxacin (64.3%), Levofloxacin (57.1%). Conclusions: Antibiotic resistance among bacteria causing urinary tract infections is increasing. Therefore, in the treatment of UTIs, current clinicians need to pay attention to following treatment instructions to avoid increasing the level of drug resistance of bacteria to achieve optimal treatment results. pros.

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