Khảo sát giá trị thang điểm ALBI, PALBI ở bệnh nhân xơ gan tại khoa nội gan mật Bệnh viện E=Investigation of ALBI and PALBI scores in cirrhosis patients at the hepatology department of E Hospital

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Tác giả: Minh Thuỷ Hán, Ngọc Đại Lâm Nguyễn, Phương Mai Nguyễn, Thị Bình Minh Nguyễn, Việt Sơn Vũ

Ngôn ngữ: vie

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Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.158-164

Bộ sưu tập: Metadata

ID: 243774

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Khảo sát chỉ số ALBI và PALBI ở bệnh nhân xơ gan tại Khoa Nội gan mật Bệnh viện E và đánh giá ý nghĩa của chỉ số ALBI và PALBI với biến chứng xuất huyết tiêu hóa do vỡ giãn tĩnh mạch thực quản. Đối tượng và phương pháp: Nghiên cứu mô tả, cắt ngang trên 135 bệnh nhân xơ gan tại Khoa Nội Gan mật Bệnh viện E từ tháng 1/2023 đến hết tháng 6/2024. Kết quả: Giá trị trung bình của chỉ số ALBI là - 1,4±0,657
thường gặp ở ALBI nhóm 3 (48,9%). Giá trị trung bình của chỉ số PALBI là -1,93 ± 0,55, thường gặp ở PALBI nhóm 3 (73,3%). Chỉ số ALBI, PALBI có mối tương quan tuyến tính chặt chẽ với thang điểm Child-Pugh, có ý nghĩa thống kê p<
0,001.Diện tích dưới đường cong ROC của ALBI và PALBI với biến chứng xuất huyết tiêu hóa lần lượt là 0,468 và 0,491. Có sự khác biệt giữa các phân nhóm PALBI với biến chứng xuất huyết tiêu hóa và các biến chứng khác của xơ gan, với p<
0,05. Kết luận: Thang điểm ALBI, PALBI có tương quan tốt với thang điểm Child-Pugh trong đánh giá chức năng gan. Có mối liên quan giữa các phân nhóm PALBI với biến chứng XHTH và các biến chứng xơ gan khác. Bước đầu chưa tìm thấy giá trị dự báo biến chứng XHTH do vỡ giãn TMTQ của ALBI, PALBI.To investigate the ALBI and PALBI indices in cirrhotic patients at the Hepatology Department of E Hospital and assess their significance in predicting gastrointestinal bleeding from esophageal variceal rupture. Subjects and methods: A descriptive crosssectional study was conducted on 135 cirrhotic patients at E Hospital from January 2023 to June 2024. Results: The mean of ALBI was - 1,4±0,657, most common in ALBI group 3 (48,9%). The mean of PALBI was -1,93±0,55, most common in PALBI group 3 (73,3%). Both indices strongly correlated with the Child-Pugh score (p<
0.001). The AUC for ALBI and PALBI concerning gastrointestinal bleeding were 0,468 and 0,491, respectively. Differences were found between PALBI subgroups and bleeding and other cirrhosis complications (p<
0,05). Conclusion: ALBI and PALBI scores correlated well with the Child-Pugh score in assessing liver function. PALBI subgroups were linked to bleeding and other cirrhosis complications, but neither ALBI nor PALBI predicted bleeding from variceal rupture.

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