Mối liên quan giữa nồng độ NT-proBNP huyết thanh với một số đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị ở bệnh nhân đợt cấp bệnh phổi tắc nghẽn mạn tính=Relationship between serum NT-proBNP levels and clinical, paraclinical features and outcomes in patients with exacerbation of chronic obstructive pulmonary disease

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Thị Duyên Bùi, Thị Vân Anh Phạm, Khánh Chi Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.103-109

Bộ sưu tập: Metadata

ID: 243796

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Đánh giá mối liên quan giữa nồng độ NT-proBNP huyết thanh với một số đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị ở bệnh nhân đợt cấp bệnh phổi tắc nghẽn mạn tính (BPTNMT). Đối tượng và phương pháp: nghiên cứu mô tả cắt ngang trên 82 bệnh nhân được chẩn đoán đợt cấp BPTNMT điều trị tại Khoa Nội tiết - Hô hấp và Khoa Cấp cứu và Hồi sức tích cực, Bệnh viện Đại học Y Hà Nội. Kết quả: Nồng độ NT-proBNP có liên quan với mức độ nặng đợt cấp BPTNMT theo đề xuất Rome và suy tim EF <
50% ở bệnh nhân đợt cấp BPTNMT. Nhóm bệnh nhân có nồng độ NTproBNP >
125 pg/mL có nồng độ TroponinT trung bình, ALĐMP trung bình, tỷ lệ bệnh nhân đặt nội khí quản, thông khí áp lực dương không xâm nhập và tỷ lệ điều trị tại ICU cao hơn nhóm bệnh nhân có nồng độ NT-proBNP <
125 pg/mL. Kết luận: Bệnh nhân đợt cấp BPTNMT, nồng độ NT-proBNP tăng cao có liên quan đến tình trạng nặng, có nguy cơ cần điều trị tại ICU và các can thiệp điều trị suy hô hấp. Điều này có ý nghĩa trong tiên lượng, theo dõi và dự phòng các biến chứng nặng cho bệnh nhân.To assess the relationship between serum NT-proBNP levels and clinical, paraclinical features and outcomes in acute exacerbation of chronic obstructive pulmonary disease. Subjects and Methods: A crosssectional descriptive study was conducted on 82 patients diagnosed acute exacerbation of chronic obstructive pulmonary disease hospitalized by Department of Endocrinology-Respiratory Medicine and Department of Emergency Medicine and Intensive Care, Hanoi Medical University Hospital. Results: In patients with acute exacerbations of chronic obstructive pulmonary disease, NT-proBNP levels were associated with the severity according to the Rome proposal and heart failure EF<
50%. In patients with NT-proBNP levels >
125 pg/mL, mean Troponin T levels, mean pulmonary artery pressure, the proportion of patients intubated, noninvasive positive pressure ventilation and the proportion of patients treated in the ICU were higher. Conclusion: In patients with acute exacerbations of chronic obstructive pulmonary disease, elevated NT-proBNP levels were associated with the severity and they were at rick of ICU treatment and respiratory failure interventions. This is meaningful in monitoring, predicting, and prevention of serious complications for patients.

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