Mô tả nguy cơ bệnh động mạch vành bằng nồng độ troponin I siêu nhạy ở người bệnh không có triệu chứng tại Bệnh viện Đa khoa Hoàn Mỹ Minh Hải năm 2023-2024=Describe the risk of coronary artery disease with high sensitive troponin I concentrations in asymptomatic patients at Hoan My Minh Hai General Hospital in 2023-2024

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Tác giả: Trung Hiếu Lê, Hồng Hạt Nguyễn, Việt Triều Nguyễn, Văn Hùng Phan

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.65-71

Bộ sưu tập: Metadata

ID: 243810

Thêm vào giỏ

Phân loại bệnh động mạch vành bằng nồng độ troponin I siêu nhạy ở những người bệnh không có triệu chứng bệnh động mạch vành góp phần giảm biến cố tương lai. Mục tiêu nghiên cứu: 1) Mô tả nguy cơ bệnh động mạch vành bằng nồng độ troponin I siêu nhạy ở người bệnh không có triệu chứng. 2) Tương quan giữa phân loại nguy cơ bệnh động mạch vành bằng nồng độ troponin I siêu nhạy với ước tính nguy cơ 10 năm bằng thang điểm Framingham. Đối tượng và phương pháp nghiên cứu: Nghiên cứu cắt ngang 1295 người bệnh không có triệu chứng bệnh động mạch vành từ 1/2023 đến 3/2024. Đánh giá nguy cơ bệnh động mạch vành bằng xét nghiệm troponin I siêu nhạy. Sau đó, đánh giá tương quan với ước tính bằng thang điểm Framingham. Kết quả: phân loại thấp chiếm 63,9% trung vị 1,9 (1-2,9)pg/mL, trung bình chiếm 21,1% trung vị 6,4 (5,05-8,3) pg/mL, cao chiếm 15% trung vị 21 (13,8-37) pg/mL. Hệ số tương quan giữa nguy cơ bệnh động mạch vành bằng nồng độ troponin I siêu nhạy với ước tính bằng thang điểm Framingham: nguy cơ thấp có rs=0,33 (p=0,001), trung bình rs=0,28 (p=0,001), cao rs=-0,04 (p=0,68). Kết luận: Hầu hết người bệnh không có triệu chứng có nguy cơ bệnh động mạch vành thấp tỷ lệ 63,9%. Tương quan thuận giữa 2 phương pháp là thấp với hệ số tương quan rs=0,35 (p<
0,05).Risk stratification of coronary artery disease using hight sensitive troponin I levels in asymtomatic patients contributes to reducing future cardiovascular events. Objectives: 1) Describe the risk of coronary artery disease using ultra-sensitive troponin I levels in asymptomatic patient. 2) Correlation between 2 methods of estimating risk of coronary artery disease: ultra-sensitive troponin I concentration versus Framingham score. Materials and methods: Cross-sectional study of 1295 asymtomatic patients of coronary artery disease from 01/2023 to 03/2024. Assess the risk of coronary artery disease using the hight sensitive troponin I test. Examine the correlation of troponin I and Framingham score in estimating risk of coronary artery disease. Results: Using troponin I in risk stratification of asymtomatic patient of coronary artery disease, low risk group accounts for 63,9%, with median of 1,9 (1-2,9)pg/mL, medium risk group is 21,1% with median of 6,4 (5,05-8,3)pg/mL, high risk group is 15% with median of 21 (13,8-37)pg/mL. Correlation coefficients between the 2 methods estimating risk of coronary heart disease are rs=0,33 (p=0,001) in low risk group
rs=0,28 (p=0,001) in medium risk group
and rs=-0,04 (p=0,68) in high risk group. Conclusion: Most asymptomatic patients have a low risk of coronary artery disease (63,9%). The positive correlation between the two methods is low with correlation coefficient rs=0,35 (p<
0,05).

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