Nghiên cứu mối liên quan giữa nồng độ peptide natriuretic type B (BNP) máu với một số chỉ số chức năng tim trên siêu âm ở bệnh nhân suy tim=Relationship between blood B type natriuretic peptide (BNP) concentration and some cardiac function indices on ultrasound in patients with heart failure

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Tác giả: Thị Ánh Dương Bùi, Quang Huy Dương, Duy Toàn Nguyễn, Thị Quỳnh Giang Nguyễn, Thái Bình Phạm, Văn Trân Phạm

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.59-64

Bộ sưu tập: Metadata

ID: 243813

Thêm vào giỏ

Analyze the relationship between B-type natriuretic peptide (BNP) levels and cardiac function in patients with heart failure (HF) in 103 Military Hospital. Subjects and methods: HF patients (n = 150) and 50 healthy volunteers were included in the study. Fasting venous blood was taken and anticoagulated with heparin to quantify BNP levels. The association between blood BNP levels and cardiac function in heart failure patients was analyzed using Pearson's correlation analysis. Results: BNP levels in the blood of HF patients were higher than those of healthy controls. Compared with the control group, the HF patient group had higher LAD, LVDs, LVDd, uric acid, troponin I (TnI), and CK-MB levels but lower LVEF and hemoglobin (Hb). Conclusion: Blood BNP levels in heart failure patients correlate with cardiac function indices on ultrasound.Phân tích mối liên quan giữa nồng độ BNP với một số chỉ số chức năng tim trên siêu âm ở bệnh nhân suy tim (heart failure - HF) tại Bệnh viện Quân Y 103. Đối tượng và phương pháp: Bệnh nhân HF (n = 150) và 50 người tình nguyện khỏe mạnh được đưa vào nghiên cứu. Lấy máu tĩnh mạch lúc đói, chống đông bằng heparin định lượng nồng độ BNP. Mối liên quan giữa nồng độ BNP trong máu và chức năng tim ở bệnh nhân suy tim được phân tích bằng phân tích tương quan của Pearson. Kết quả: Nồng độ BNP trong máu của bệnh nhân HF cao hơn so với nhóm chứng khỏe mạnh. So với nhóm chứng, nhóm bệnh nhân HF có LAD, LVDs, LVDd, nồng độ acid uric, troponin I (TnI) và CK-MB cao hơn, nhưng LVEF, nồng độ hemoglobin (Hb) thấp hơn. Kết luận: Nồng độ BNP máu ở bệnh nhân suy tim có tương quan với các chỉ số chức năng tim trên siêu âm.

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