Thực trạng báo cáo phản ứng có hại của thuốc chống lao tại Bệnh viện Phổi Thái Bình giai đoạn 2017 - 2021=Review of adverse drug reactions of antituberculosis drugs reported at Thai Binh Lung Hospital over the period 2017 to 2021

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Tác giả: Thị Tuyết Lan Đinh, Thị Duyên Ngô, Thị Châu Loan Nguyễn, Thị Hồng Thịnh Tô

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Y Dược Thái Bình (Đại học Y Dược Thái Bình), 2024

Mô tả vật lý: tr.85-91

Bộ sưu tập: Metadata

ID: 244001

Thêm vào giỏ

Mô tả thực trạng báo cáo phản ứng có hại của thuốc chống lao tại Bệnh viện Phổi Thái Bình giai đoạn 2017 - 2021. Phương pháp: Nghiên cứu hồi cứu từ các báo cáo phản ứng có hại của thuốc thu thập được trong giai đoạn 2017 - 2021 lưu trữ tại Khoa Dược, Bệnh viện Phổi Thái Bình. Kết quả: 80,4% báo cáo ADR của thuốc chống lao
75,7% bệnh nhân là nam giới và 57,0% bệnh nhân trong nhóm tuổi từ 18-60 tuổi
Tubezid là chế phẩm thuốc nghi ngờ gây ADR cao nhất (44,9%). Tỷ lệ ADR thường gặp là rối loạn trên da và tổ chức dưới da (biểu hiện về lâm sàng) như: ngứa, mẩn đỏ và tăng men gan (biểu hiện về cận lâm sàng) với tỷ lệ tương ứng là 57,5%
2,2%. Đa số các ADR không nghiêm trọng, chiếm 94,2%
Báo cáo ADR có chất lượng tốt chiếm 58,1%. Ngừng thuốc là biện pháp xử trí ADR thường gặp, chiếm 88,4%. Sau xử trí, 100% bệnh nhân có hồi phục.To describe the current situation of Adverse Drug Reaction report’s antituberculosis drugs at Thai Binh Lung Hospital from 2017 to 2021. Method: Retrospective study on all reports of Adverse Drug Reactions antituberculosis drugs at Faculty of Pharmacy, Thai Binh Lung Hospital from 2017 to 2021. Results: 80,4% of Adverse Drug Reaction (ADR) reports was involved antituberculosis drugs. 75,7% of patients were male and 57,0% of patients were 18-60 years. Tubezid was the most common drug reported induced ADRs (44,9%). The most frequent symptoms were skin and subcutaneous tissue disorders such as: itchy, redness skin (in clinical symptoms) and increasing hepatic enzyme (in subclinical symptoms) respectively 57,5%
2,2%. 94,2% of ADRs weren’t serious and 58,1% of reports were good quality. When ADRs were occurred, the most common therapy wasn’t using suspected drug (88,4%). 100% of patients were recovered after treatment.

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