So sánh hiệu quả dự phòng buồn nôn–nôn của Ondansetron sau gây mê cho phẫu thuật vùng mặt, cổ=Comparison of the effectiveness of Ondansetron in preventing nausea and vomiting after anesthesia for facial and neck surgery

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Đức Chính Bùi, Thị Yến Bùi, Lê Phi Bách Hoàng, Thị Ngọc Hiền Huỳnh, Thị Hà Vy Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Y Dược Thái Bình (Đại học Y Dược Thái Bình), 2024

Mô tả vật lý: tr.4-10

Bộ sưu tập: Metadata

ID: 244495

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Đánh giá hiệu quả dự phòng buồn nôn–nôn và khảo sát các tác dụng không mong muốn của Ondansetron xảy ra trên người bệnh khi dự phòng buồn nôn–nôn sau gây mê toàn thân để phẫu thuật vùng mặt, cổ. Phương pháp nghiên cứu: Nghiên cứu tiến cứu, có đối chứng. Nghiên cứu trên 60 người bệnh có chỉ định gây mê nội khí quản để phẫu thuật vùng mặt cổ, phân bố ngẫu nhiên vào hai nhóm: Nhóm CO được tiêm dự phòng Ondansetron 4 mg ngay sau khi kết thúc phẫu thuật
nhóm KO không tiêm dự phòng Ondansetron. Kết quả: Tỷ lệ người bệnh buồn nôn–nôn sau gây mê phẫu thuật 24 giờ ở nhóm CO (10%) thấp hơn so với nhóm KO (50%). Tỷ lệ người bệnh cần sử dụng thuốc chống nôn Primerane ở nhóm CO là 10%, ở nhóm KO là 40%. Nhóm CO không ghi nhận tác dụng không mong muốn nghiêm trọng nào xảy ra.Kết luận: Phương pháp tiêm tĩnh mạch 4 mg Ondansetron ngay sau kết thúc phẫu thuật giúp giảm tình trạng buồn nôn–nôn trên người bệnh sau gây mê toàn thân để phẫu thuật vùng mặt, cổ, ít xảy ra các tác dụng không mong muốn.To evaluate the effectiveness of Ondansetron in preventing nausea-vomiting and investigate the undesirable effects of Ondansetron occurring in patients after general anesthesia for maxillofacial and neck surgery. Method: Prospective controlled trial study. 60 patients with endotracheal anaesthesia who managed to do maxillofacial and neck surgery were randomly assigned to two groups: Group CO received a prophylactic injection of Ondansetron 4 mg right after the end of surgery
group KO was not received Ondansetron vaccination. Results: The proportion of patients who suffering from nausea–vomiting within 24 hours after surgical anesthesia in the CO group (10%) was lower than in the KO group (50%). The proportion of patients who needed to use antiemetic Primerane in the CO group was 10%, in the KO group it was 40%. There is no serious adverse effects were recorded in the CO group. Conclusions: The method of intravenous injection of 4 mg Ondansetron right after the surgery minimizes nausea-vomiting in patients after general anesthesia for maxillofacial and neck surgery
side effects are less likely to occur.

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