Nghiên cứu đặc điểm lâm sàng và cận lâm sàng của bệnh nhân vô hạch toàn bộ đại tràng được phẫu thuật nội soi theo phương pháp Duhamel tại Bệnh viện Nhi Trung ương từ 2013 - 2018=Clinical and paraclinical characteristics of patients with total colonic aganglionosis undergoing laparoscopy by Duhamel procedure at the National Children's Hospital from 2013 to 2018

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Tác giả: Hữu Kiên Hoàng, Anh Quỳnh Trần, Hùng Trần, Văn Trung Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu y học (Đại học Y Hà Nội), 2024

Mô tả vật lý: tr.65-70

Bộ sưu tập: Metadata

ID: 244627

Thêm vào giỏ

Bệnh vô hạch toàn bộ đại tràng là một thể bệnh nặng, ít gặp trong vô hạch thần kinh đường tiêu hóa. Việc đáng giá đầy đủ các triệu chứng lâm sàng, cận lâm sàng giúp cho việc điều trị được thuận lợi. Nghiên cứu nhằm mô tả đặc điểm lâm sàng, cận lâm sàng bệnh nhân vô hạch toàn bộ đại tràng được phẫu thuật nội soi theo phương pháp Duhamel tại Bệnh viện Nhi Trung ương từ 2013 - 2018. Nghiên cứu được tiến hành theo phương pháp mô tả hồi cứu loạt ca bệnh với 33 bệnh nhân được phẫu thuật nội soi hỗ trợ điều trị vô hạch toàn bộ đại tràng bằng kĩ thuật Duhamel. Kết quả nghiên cứu cho thấy tỷ lệ nam/nữ là: 1,7/1. Tất cả bệnh nhân được chẩn đoán xác định dựa vào kết quả sinh thiết không có hạch thần kinh ở đại tràng và hồi tràng được phẫu thuật làm dẫn lưu hồi tràng. Tắc ruột sơ sinh hoặc viêm phúc mạc sơ sinh (81,8%). Biến chứng hay gặp là viêm trợt da quanh dẫn lưu hồi tràng (30,3%), sa dẫn lưu hồi tràng (15,2%) và tỷ lệ bệnh nhân suy dinh dưỡng trước phẫu thuật cao (33,3%). Nghiên cứu cho thấy các đặc điểm lâm sàng và cận lâm sàng ở bệnh nhân vô hạch toàn bộ đại tràng, phục vụ cho quá trình điều trị và phẫu thuật trong tương lai.Total colon aganglionosis (TCA) is a serious, rare form of gastrointestinal aganglionosis. Full assessment of clinical and paraclinical symptoms facilitates treatment. The purpose of this study was to describe the clinical and paraclinical characteristics of TCA patients undergoing laparoscopic assisted with Duhamel procedure at the National Children's Hospital from 2013 to 2018. This was a retrospective descriptive method of 33 patients undergoing laparoscopic assisted with the Duhamel procedure. Research results show that the male/female ratio was 1.7/1. All patients were diagnosed based on biopsy results without nerve nodes in the colon and ileum and underwent ileostomy. Neonatal intestinal obstruction or neonatal peritonitis represented 81.8%. Common complications were erosive dermatitis around the ileostomy (30.3%), intestinal prolapse (15.2%), and a high rate of malnutrition in patients prior to surgery (33.3%). The study shows clinical and paraclinical characteristics in patients with TCA, serving future treatment and surgery.

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