Liên quan giữa nồng độ 25-Hydroxyvitamin D với đặc điểm lâm sàng, cận lâm sàng ở trẻ mới chẩn đoán đái tháo đường týp 1 tại Bệnh viện Nhi Trung ương=Relationship between 25-Hydroxyvitamin D concentrations and clinical, laboratory characteristics of children newly diagnosed with type 1 diabetes mellitus at Vietnam National Children's Hospital

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Tác giả: Phương Thảo Bùi, Thị Phương Mai Chu, Ngọc Khánh Nguyễn, Thị Linh Nguyễn, Thị Thuý Hồng Nguyễn, Thu Nga Phạm, Chí Dũng Vũ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu y học (Đại học Y Hà Nội), 2024

Mô tả vật lý: tr.71-78

Bộ sưu tập: Metadata

ID: 244628

Thêm vào giỏ

Children newly diagnosed with type 1 diabetes mellitus are at risk of vitamin D deficiency, especially children with ketoacidosis complications. This cross-sectional descriptive study on 33 newly diagnosed with type 1 diabetes at Vietnam National Children's Hospital investigated the relationship between 25-hydroxyvitamin D levels and several factors. The rate of children deficiency or insufficient vitamin D (25(OH)D ≤ 50 nmol/L) is 60.6%, especially children with ketoacidosis complications at the time of diagnosis.There was no relationship between 25(OH)D concentration and HbA1c, glucose, C-peptide, and the number of autoantibodies. Vitamin D deficiency or insufficient is common in children newly diagnosed with type 1 diabetes, especially children with ketoacidosis complications.Trẻ mới chẩn đoán đái tháo đường týp 1 có nguy cơ thiếu hụt vitamin D, đặc biệt là trẻ có biến chứng toan ceton. Nghiên cứu mô tả cắt ngang trên 33 trẻ mới chẩn đoán đái tháo đường týp 1 tại Bệnh viện Nhi Trung ương khảo sát mối liên quan giữa nồng độ 25-hydroxyvitamin D và một số yếu tố. Tỷ lệ trẻ thiếu/ không đủ vitamin D (25(OH)D ≤ 50 nmol/L) là 60,6%, đặc biệt trẻ có biến chứng toan ceton tại thời điểm chẩn đoán có nồng độ 25(OH)D thấp hơn so với nhóm không có toan ceton. Không nhận thấy mối liên quan giữa nồng độ 25(OH)D và HbA1c, glucose, C-peptide và số lượng tự kháng thể. Tình trạng thiếu/không đủ vitamin D thường gặp ở trẻ mới chẩn đoán đái tháo đường týp 1, đặc biệt là trẻ có biến chứng toan ceton.

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