Nguy cơ hội chứng nuôi ăn lại và một số yếu tố liên quan ở người bệnh ung thư thực quản xét chỉ định xạ trị=Risk of refeeding syndrome and related factors in esophageal cancer considering radiotherapy treatment

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Minh Nhật Nguyễn, Quang Duy Nguyễn, Thị Thanh Nguyễn, Trung Bách Trần, Văn Xuân Võ, Xuân Huy Vũ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu y học (Đại học Y Hà Nội), 2024

Mô tả vật lý: tr.133-141

Bộ sưu tập: Metadata

ID: 244670

Thêm vào giỏ

A cross-sectional descriptive study was performed on 132 esophageal cancer patients at Tan Trieu General Radiotherapy Department of Vietnam National Cancer Hospital from March 2022 to March 2024 to evaluate the risk of developing refeeding syndrome at the time of considering radiation therapy indication. Median age at diagnosis was 60.7, male:female ratio was 131:1, 100% patients were diagnosed with squamous cell carcinoma. The majority of patients had upper third esophageal tumors (74.3%) and in locally advanced or metastatic stage (stage III-IV, 87.1%). The high risk rate of developing refeeding syndrome according to the standards of the UK National Institute for Healthcare Excellence (NICE) in 2017 was 29.5%. The length of the primary tumor (cut-off threshold was 6.7cm), grade 2 or more, dysphagia, weight loss at admission and enteral tube feeding through percutaneous gastrostomy were factors associated with high risk of developing refeeding syndrome (p <
0.05).Nghiên cứu mô tả cắt ngang trên 132 bệnh nhân ung thư thực quản tại Khoa Xạ trị Tổng hợp Tân Triều, Bệnh viện K từ tháng 3/2022 đến tháng 3/2024 nhằm đánh giá nguy cơ phát triển hội chứng nuôi ăn lại tại thời điểm xét chỉ định điều trị xạ trị. Tuổi chẩn đoán trung vị là 60,7, tỷ lệ nam:nữ là 131:1, 100% có mô bệnh học là ung thư biểu mô tế bào vảy. Đa số bệnh nhân có u thực quản ở vị trí 1/3 trên (74,3%) và khi chẩn đoán đã ở giai đoạn bệnh tiến triển tại chỗ - tại vùng hoặc di căn (giai đoạn III - IV, 87,1%). Tỷ lệ nguy cơ cao phát triển hội chứng nuôi ăn lại theo tiêu chuẩn của Viện chăm sóc sức khỏe chất lượng cao Quốc gia Anh (NICE) năm 2017 là 29,5%. Chiều dài khối u nguyên phát (với ngưỡng cut-off là 6,7cm), nuốt nghẹn từ độ 2 trở lên, có sút cân khi vào viện và ăn qua sonde mở thông dạ dày là các yếu tố có liên quan nguy cơ cao phát triển hội chứng nuôi ăn lại (p <
0,05).

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