Đặc điểm kháng kháng sinh của các vi khuẩn gây nhiễm khuẩn huyết thường gặp tại Bệnh viện Bệnh nhiệt đới Trung ương năm 2022 - 2023=Antibiotic resistance characteristics of some common bacteria causing sepsis at the National Hospital of Tropical Diseases (2022

Đặc điểm kháng kháng sinh của các vi khuẩn gây nhiễm khuẩn huyết thường gặp tại Bệnh viện Bệnh nhiệt đới Trung ương năm 2022 - 2023=Antibiotic resistance characteristics of some common bacteria causing sepsis at the National Hospital of Tropical Diseases (2022 - 2023)

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Quốc Phương Nguyễn, Văn Giang Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu y học (Đại học Y Hà Nội), 2024

Mô tả vật lý: tr.419-428

Bộ sưu tập: Metadata

ID: 244694

Thêm vào giỏ

Nghiên cứu được thực hiện nhằm mô tả đặc điểm kháng kháng sinh của các vi khuẩn gây nhiễm khuẩn huyết thường gặp tại Bệnh viện Bệnh Nhiệt đới Trung ương, từ 1/2022 đến 12/2023. Có 117 bệnh nhân được chẩn đoán là nhiễm khuẩn huyết và xác định được căn nguyên vi khuẩn trong thời gian nghiên cứu. Kết quả: tuổi trung bình của bệnh nhân trong nghiên cứu là 56,82 ± 15,92 , nam là 66,7%. Đường vào chủ yếu là đường hô hấp là 22,2%, da/mô mềm là 10,3%, tiêu hóa là 9,4%, tiết niệu là 8,5%. Nhiễm khuẩn huyết mắc phải trong cộng đồng là 61,6 %, vi khuẩn Gram dương chiếm 53,8%. Ba căn nguyên vi khuẩn thường gặp gây nhiễm khuẩn huyết là E. coli (26,5%)
S. aureus (23,1%), K. pneumoniae (12%). Kết quả kháng sinh đồ cho thấy E. coli kháng các kháng sinh trong nhóm Cephalosporin từ 20 % - 50%, kháng các kháng sinh trong nhóm Quinolon từ 25% - 46,9%, kháng amikacin 7,2%, nhạy 100% với các kháng sinh nhóm carbapenem. K. pneumoniae kháng Ampicillin là 100%, kháng các kháng sinh nhóm carbapenem từ 6,7 % - 13,3%, kháng các kháng sinh trong nhóm cephalosporin từ 14,3% - 27,3Trường Đại học Y Hà Nội%, kháng ciprofloxacin 40%, kháng amikacin 7,2%. S. aureus: MRSA là 82,6%, VRA là 3%, kháng 100% với Penicillin, kháng clindamycin 87,1%.The study was conducted to describe the antibiotic resistance characteristics of some common bacteria causing sepsis at the National Hospital of Tropical Diseases from January 2022 to December 2023. During the study period, 117 patients were diagnosed with sepsis, and the bacterial causes were identified. Results: the average age of patients in the study was 56.82 ± 15.92, with males accounting for 66.7%. The primary routes of admission were respiratory 22.2%, skin/soft tissue 10.3%, gastrointestinal 9.4%, and urinary 8.5%. Community-acquired bacteremia was 61.6%, Gram-positive bacteria account for 53.8%. The three most common bacterial pathogens were E. coli (26.5%), S. aureus (23.1%), and K. pneumoniae (12%). Antibiogram results showed that E. coli was 20% - 50% resistant to antibiotics in the Cephalosporin, 25% - 46.9% resistant to antibiotics in the Quinolone group, 7.2% resistant to amikacin and 100% sensitivity to antibiotics in the Carbapenem. K. pneumoniae was 100% resistant to Ampicillin, 6.7% - 13.3% carbapenem resistant, 14.3% - 27.3% cephalosporin resistant, 40% ciprofloxacin resistant, 7.2% amikacin resistant. S. aureus: MRSA was 82.6%, VRA was 3%, 100% resistance to penicillin and 87.1% resistance to clindamycin.

1. Đọc trực tuyến

1. Đọc trực tuyến

Tạo bộ sưu tập với mã QR