Một số đặc điểm dịch tễ học và tổn thương mô bệnh học tim ở nhóm người trẻ tuổi chết đột ngột do tim=Epidemiological and histopathological characteristics of cardiac lesions in young sudden cardiac death

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Tác giả: Dương Quốc Uy Âu, Sỹ Hùng Lưu, Tất Thọ Nguyễn, Xuân Hà Trịnh

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu y học (Đại học Y Hà Nội), 2024

Mô tả vật lý: tr.117-125

Bộ sưu tập: Metadata

ID: 244709

Thêm vào giỏ

A cross-sectional study was conducted on 113 cases of SCD in young people. Autopsy was performed at the Military Medicine Institute, Hanoi Center for Forensic Medicine, Ho Chi Minh City Center for Forensic Medicine and the Department of Legal Medicine, Hanoi Medical University. The study period was from January 2022 to December 2023. The majority of the cases were males (86.7%). The highest rate of SCD was observed in the 31 - 40 age group (53%), with an average age of 31 ± 7.7 years. Myocardial lesions and coronary atherosclerosis were concentrated in the 21 - 30 and 31 - 40 age groups (p = 0.004) and were more prevalent in males (p = 0.144). In 38 cases (33.6%) of SCD with no apparent myocardial lesions on histology, genetic arrhythmia syndrome (SADS) was suspected. Genetic testing is recommended for cases of SCD in young people without structural lesions on histology.Nghiên cứu cắt ngang về chết đột ngột do tim (CĐNDT) ở người trẻ tuổi (1 đến 40 tuổi) qua khám nghiệm tử thi, trong thời gian 2 năm (1/2022 - 12/2023). Nghiên cứu thực hiện ở 113 nạn nhân chết đột ngột do tim được khám nghiệm tại Viện Pháp y Quân đội, Trung tâm Pháp y Hà Nội và Trung tâm Pháp y Thành phố Hồ Chí Minh và Bộ môn Y Pháp, Trường Đại học Y Hà Nội. Các đối tượng chủ yếu là nam giới (86,7%). Độ tuổi 31 đến 40 có tỷ lệ chết đột ngột do tim cao nhất (53%), tuổi trung bình của nạn nhân là 31 ± 7,7. Tổn thương cơ tim và xơ vữa động mạch vành tập trung ở 2 nhóm tuổi 21-30 và 31- 40 có ý nghĩa thống kê (p = 0,004) và phân bố nhiều hơn ở nam giới tuy chưa có ý nghĩa thống kê (p = 0,144). 38 trường hợp (33,6%). Chết đột ngột do tim chưa thấy rõ tổn thương tim trên mô bệnh học có thể nghĩ đến hội chứng rối loạn nhịp tim di truyền (SADS). Cần thực hiện xét nghiệm gene đối với các trường hợp CĐN ở người trẻ tuổi không có tổn thương thực thể trên mô bệnh học.

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