Đặc điểm lâm sàng, cận lâm sàng 15 ca đầu tiên can thiệp sửa van hai lá qua da bằng kỹ thuật Mitraclip tại viện tim mạch quốc gia Việt Nam=Clinical and paraclinical characteristics of the first fifteen-cases of percutaneous mitral valve repair in a single center in Vietnam

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Tác giả: Huỳnh Linh Đinh, Văn Thăng Lê, Lan Anh Nguyễn, Ngọc Quang Nguyễn, Thị Thu Hoài Nguyễn, Mạnh Hùng Phạm, Nhật Minh Phạm, Tuấn Đạt Phan

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu y học (Đại học Y Hà Nội), 2024

Mô tả vật lý: tr.144-154

Bộ sưu tập: Metadata

ID: 244716

Thêm vào giỏ

Can thiệp sửa van hai lá qua da điều trị bệnh lý hở van hai lá đã và đang phát triển mạnh mẽ trên toàn thế giới, tuy nhiên thủ thuật này chưa được tiến hành nhiều tại Việt Nam. Nghiên cứu thực hiện với mục tiêu cung cấp những dữ liệu về đặc điểm lâm sàng, cận lâm sàng của các ca bệnh đầu tiên được thực hiện thủ thuật Mitraclip tại Việt Nam. Thiết kế nghiên cứu mô tả cắt ngang trên 15 bệnh nhân đầu tiên thực hiện can thiệp Mitraclip tại Viện tim mạch quốc gia Việt Nam, nhằm cung cấp một số đặc điểm lâm sàng, cận lâm sàng của nhóm bệnh nhân này. Tuổi trung bình của các bệnh nhân nghiên cứu là 68,0 ± 7,4. Tất cả bệnh nhân nghiên cứu đều có triệu chứng khó thở từ NYHA II trở lên tại thời điểm nhập viện. Đa số các bệnh nhân có nhiều bệnh lý đi kèm, bao gồm gồm tăng huyết áp (40,0%), bệnh động mạch vành hoặc tiền sử PCI (26,7%), rung nhĩ (26,7%) và bệnh thận mạn tính (20,0%). Tất cả các bệnh nhân nghiên cứu đều có tình trạng hở van hai lá mức độ nặng (độ 4+) trên siêu âm, tuy nhiên, chức năng tâm thu thất trái còn bảo tồn (LVEF trung bình 60,0 ± 13,7%). Thoái hoá van là nguyên nhân chủ yếu hở van hai lá ở các bệnh nhân nghiên cứu (chiếm 80%). Phần lớn bệnh nhân có nguy cơ phẫu thuật trung bình theo phân loại STS (điểm nguy cơ STS trung bình là 3,56 ± 3,9%). Đây là nghiên cứu đầu tiên tại Việt Nam về đặc điểm của các bệnh nhân hở van hai lá được can thiệp qua da bằng kỹ thuật Mitraclip.Introduction: Percutaneous mitral valve repair intervention to treat mitral valve regurgitation are rapidly increasingly worldwide, but remains limited in Vietnam. The study aims to provide data on the clinical and paraclinical characteristics of the first cases undergoing the Mitraclip procedure in Vietnam. Patients and Methods: This cross - sectional study focused on the first 15 patients undergoing Mitraclip intervention at the Vietnam National Heart Institute, aiming to provide clinical and paraclinical characteristics of this group of this patient cohort. Results: The average age of the patients was 68.0 ± 7.4. All patients presented with symptoms of dyspnea NYHA II and above upon admission. The majority had multiple comorbidities, including hypertension (40.0%), coronary artery disease or history of PCI (26.7%), atrial fibrillation (26.7%), and chronic kidney disease (20.0%). Ultrasonography examination revealed severe mitral valve regurgitation (grade 4+) in all patients, while left ventricular systolic function remained preserved (average LVEF 60.0 ± 13.7% ). Degenerative valve disease was the primary cause of mitral regurgitation (80%). Most patients had an intermediate surgical risk according to the STS classification (mean STS risk score was 3.56 ± 3.9%). Conclusion: This is the first study in Vietnam on the characteristics of patients with mitral regurgitation who underwent Mitraclip procedure.

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