Đánh giá tác dụng kéo dài giảm đau sau mổ bằng dexamethasone phối hợp Ropivacain trong gây tê mặt phẳng cơ dựng sống cho phẫu thuật cột sống thắt lưng=Evaluation of the prolonged postoperative analgesic effect of dexamethasone combined with ropivacaine in erector spinae planal block for lumbar spine surgery

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Tác giả: Nữ Diệp Anh Dương, Thị Hồng Nhung Tống, Hoàng Phương Vũ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu y học (Đại học Y Hà Nội), 2024

Mô tả vật lý: tr.36-44

Bộ sưu tập: Metadata

ID: 244731

Thêm vào giỏ

A randomized controlled clinical trial was conducted from October 2022 to September 2023 at Hanoi Medical University Hospital to investigate the prolonged postoperative analgesic effect of dexamethasone combined with ropivacaine in erector spinal plane block for lumbar spine surgery. 70 patients undergoing lumbar spine surgery were randomly assigned to receive either ropivacaine with dexamethasone or ropivacaine alone for erector spinal plane block. Result: The duration of postoperative analgesia was significantly longer in the dexamethasone group compared to the ropivacaine-only group (381.42 ± 32.65 minutes vs 203.17 ± 27.34 minutes, p <
0.05). Morphin consumption was significantly lower in the dexamethasone group during the first 24 hours after surgery (8.74 ± 3.56 mg vs 16.32 ± 6.54 mg, p <
0.05). VAS pain scores at rest and on movement were also significantly lower in the dexamethasone group at 4, 6, 8, and 12 hours post-surgery (p <
0.05). Conclusion: Dexamethasone combined with ropivacaine in erector spinal plane block provides prolonged postoperative analgesia and reduces morphine consumption in patients undergoing lumbar spine surgery.Nghiên cứu can thiệp lâm sàng ngẫu nhiên có đối chứng được thực hiện từ tháng 10/2022 - tháng 9/2023 tại Bệnh viện Đại học Y Hà Nội nhằm đánh giá tác dụng kéo dài giảm đau sau mổ bằng dexamethasone phối hợp ropivacain trong gây tê mặt phẳng cơ dựng sống cho phẫu thuật cột sống thắt lưng. 70 bệnh nhân phẫu thuật cột sống thắt lưng theo kế hoạch được giảm đau trước mổ bằng gây tê mặt phẳng cơ dựng sống chia thành hai nhóm: nhóm sử dụng dexamethasone phối hợp ropivacain và nhóm ropivacain đơn thuần. Kết quả cho thấy, nhóm phối hợp dexamethsone có thời gian kéo dài giảm đau (6,35 ± 0,54 giờ) lớn hơn đáng kể so với nhóm chứng (3,38 ± 0,46 giờ), lượng morphin trong 24 giờ đầu sau phẫu thuật thấp hơn đáng kể (8,74 ± 3,56mg so với 16,32 ± 6,54mg, p <
0,05), điểm đau VAS khi nghỉ và vận động đều giảm có ý nghĩa ở các thời điểm 4, 6, 8, 12 giờ (p <
0,05). Nghiên cứu của chúng tôi cho thấy dexamethasone phối hợp với ropivacain trong gây tê mặt phẳng cơ dựng sống cho phẫu thuật cột sống thắt lưng có tác dụng kéo dài thời gian giảm đau đồng thời giảm tiêu thụ opioid.

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