Đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị ở bệnh nhân nhồi máu não cấp có bệnh lý ung thư kèm theo=Clinical features, paraclinical characteristics and treatment outcomes in patients with acute ischemic stroke and cancer pathology

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Tác giả: Việt Phương Đào, Trung Hiếu Đinh, Thị Thu Hoài Lương, Duy Tôn Mai, Anh Tuấn Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu y học (Đại học Y Hà Nội), 2024

Mô tả vật lý: tr.156-165

Bộ sưu tập: Metadata

ID: 244744

Thêm vào giỏ

Bệnh lý ung thư là một trong các yếu tố nguy cơ của đột quỵ nhồi máu não, làm tăng gánh nặng bệnh tật, tỷ lệ tử vong cũng như di chứng tàn tật ở bệnh nhân nhồi máu não. Nghiên cứu quan sát mô tả được tiến hành trên 87 bệnh nhân nhồi máu não cấp kèm theo bệnh lý ung thư tại Trung tâm Đột quỵ Bạch Mai từ tháng 01 năm 2023 đến tháng 03 năm 2024 nhằm mô tả đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị của nhóm bệnh nhân này. 87 bệnh nhân (tuổi trung bình 67,7 ± 11,7
NIHSS nhập viện 5 (3 - 8)) tham gia nghiên cứu. Ba bệnh lý ung thư phổ biến nhất là ung thư đại tràng (16,1%), ung thư tuyến giáp (14,9%) và ung thư phổi (12,6%). Triệu chứng lâm sàng thường gặp là liệt vận động (81,6%) và nói khó (71,3%). Hầu hết các bệnh nhân đều có tổn thương đa ổ, kích thước nhỏ trên phim chụp cắt lớp vi tính sọ não hoặc chụp cộng hưởng từ. Giá trị xét nghiệm D-dimer trung vị là 2,8 (1,12 - 4,10). Có 48,3% bệnh nhân có kết quả điều trị tốt (mRS 0-2). Những yếu tố liên quan tới kết quả điều trị tốt bao gồm: giới tính nam, điểm NIHSS và nồng độ D-dimer.Cancer is considered one of the risk factors for ischemic stroke, leading to an increasing health burden, mortality, and disability among acute ischemic stroke (AIS) patients. A cross-sectional study was conducted on AIS patients with cancer diseases at Bach Mai Stroke Center from January 2023 to March 2024 to describe the clinical and paraclinical characteristics and treatment outcomes of this group of patients. 87 patients (mean age 67.7 ± 11.7
median admission NIHSS score 5 (3 - 8)) were recruited. The three most common cancers were colon (16.1%), thyroid (14.9%), and lung cancer (12.6%). Hemiplegia (81.6%) and speech disturbance (71.3%) were the most prevalent clinical symptoms. Most patients had small, multifocal lesions on a brain CT or MRI. The median D-dimer value was 2.8 (1.12 - 4.10). 48.3% of patients got a good outcome (mRS 0-2). Factors associated with a good outcome included male sex, NIHSS score, and D-dimer levels.

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