Kết quả thai kỳ sau chuyển một phôi nang chuẩn bội: Một nghiên cứu hồi cứu=Pregnancy outcomes after single euploid blastocyst transfer: A retrospective study

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Tác giả: Thị Mai Phương Giáp, Đức Thắng Lê, Hoàng Lê, Minh Thúy Nguyễn, Thành Khiêm Nguyễn, Thị Mai Anh Vũ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Nghiên cứu y học (Đại học Y Hà Nội), 2024

Mô tả vật lý: tr.422-429

Bộ sưu tập: Metadata

ID: 244806

Thêm vào giỏ

A cross-sectional descriptive study with retrospective data from 387 embryo transfer cycles from January 2021 to June 2023 was conducted to evaluate pregnancy outcomes after single euploid blastocyst transfer at a reproductive center in Vietnam. Results: The pregnancy, clinical pregnancy, and live birth rates were 67.70%, 57.88%, and 48.68%, respectively. Embryo quality significantly influenced the outcomes, with higher success rates in good-quality embryos compared to fair and average quality ones (p <
0.001). However, maternal age had no significant impact (p >
0.05). The miscarriage, preterm birth, and multiple pregnancy rates were 14.29%, 7.98%, and 1.33%, respectively. Conclusion: The study demonstrated the benefits of PGT-A in improving pregnancy outcomes, especially in older patients. Transferring a single best-quality euploid blastocyst optimized success and minimized complications.Nghiên cứu mô tả cắt ngang lấy dữ liệu hồi cứu trên 387 chu kỳ chuyển phôi từ 01/2021 đến 06/2023 với mục tiêu đánh giá kết quả thai kỳ sau chuyển một phôi nang chuẩn bội tại một trung tâm hỗ trợ sinh sản ở Việt Nam. Kết quả: Tỷ lệ có thai, thai lâm sàng và sinh sống lần lượt là 67,70%, 57,88% và 48,68%. Chất lượng phôi chuyển là yếu tổ ảnh hưởng đến kết quả, với tỷ lệ thành công cao hơn đáng kể ở nhóm phôi chất lượng tốt so với phôi chất lượng khá và trung bình (p <
0,001). Tuy nhiên, tỷ lệ thành công không khác biệt giữa các nhóm tuổi mẹ (p >
0,05). Tỷ lệ sẩy thai, đẻ non và đa thai lần lượt là 14,29%, 7,98% và 1,33%. Kết luận: Nghiên cứu cho thấy lợi ích của PGT-A trong cải thiện kết quả thai kỳ, đặc biệt ở bệnh nhân lớn tuổi. Việc chuyển một phôi nang chuẩn bội với hình thái tốt nhất giúp tối ưu hóa tỷ lệ thành công và giảm thiểu biến chứng.

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