Tỷ lệ suy mòn protein năng lượng và một số yếu tố liên quan ở bệnh nhân bệnh thận mạn giai đoạn cuối=Prevalence of protein-energy wasting and some related factors in end-stage kidney disease patients

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Tác giả: Quốc Việt Lê, Huỳnh Ngọc Tân Mai, Hoàng Bảo Ngọc Nguyễn, Ngọc Hồ Trần, Thị Kim Thi Võ

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y dược học Cần Thơ, 2024

Mô tả vật lý: tr.97-104

Bộ sưu tập: Metadata

ID: 244851

Thêm vào giỏ

Hội chứng suy mòn protein năng lượng (PEW) đang ngày càng gia tăng ở bệnh nhân bệnh thận mạn giai đoạn cuối (BTMGĐC), nó ảnh hưởng xấu đến tỷ lệ tử vong, hoạt động chức năng và chất lượng cuộc sống của bệnh nhân. Mục tiêu nghiên cứu: Xác định tỷ lệ suy mòn protein năng lượng và khảo sát một số yếu tố liên quan ở bệnh nhân bệnh thận mạn đang lọc máu chu kỳ tại bệnh viện Đa khoa Thành phố Cần Thơ năm 2023. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên 329 bệnh nhân bệnh thận mạn giai đoạn cuối đang lọc máu chu kỳ tại bệnh viện Đa khoa Thành phố Cần Thơ năm 2023. Kết quả: Tỷ lệ bệnh nhân bệnh thận mạn mắc hội chứng suy mòn protein năng lượng là 31,9%. Nhóm BMI, SGA, số bệnh đồng mắc, mức độ tăng cân giữa 2 lần lọc máu có liên quan đến tỷ lệ mắc hội chứng PEW trong phân tích đơn biến. Trên mô hình hồi quy logistic đa biến, số bệnh đồng mắc, SGA, BMI, tăng cân giữa 2 lần lọc máu ≥5% có liên quan độc lập đến hội chứng PEW. Trong đó, BMI có liên quan nghịch với PEW. Kết luận: Hội chứng PEW ở bệnh nhân bệnh thận mạn giai đoạn cuối lọc máu chu kỳ chiếm tỷ lệ cao, thường xảy ra ở bệnh nhân có nhiều bệnh đồng mắc, tăng cân giữa 2 lần lọc máu ≥5%, có tình trạng dinh dưỡng kém theo SGA, BMI thấp.Protein-energy wasting (PEW) in end-stage kidney disease (ESKD) patients has increased in recent years, and affects mortality, functional activity, and quality of life of patients. Objectives: we aim to determine the rate of PEW and some related factors in ESKD patients on hemodialysis at Can Tho General Hospital. Materials and methods: A cross-sectional descriptive study was performed on a total of 329 participants with ESKD undergoing hemodialysis at Can Tho General Hospital in 2023. Results: The prevalence of PEW in ESKD patients was 31.9%. BMI, SGA, number of comorbidities, interdialytic weight gain ≥5% were associated with the prevalence of PEW in univariate analysis. In multivariable logistic analysis, BMI, SGA, number of comorbidities, interdialytic weight gain ≥5% were independent risk factors for PEW in ESKD patients on maintenance hemodialysis. BMI are inversely related to PEW. Conclusion: The rate of PEW in ESKD patients on maintenance hemodialysis was high
number of comorbidities, interdialytic weight gain ≥5%, low BMI, poor nutritional status according to SGA were independent risk factors for PEW.

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