Nghiên cứu biểu hiện, giá trị phân biệt của một số đặc điểm lâm sàng, xét nghiệm giữa nhóm sống - tử vong ở bệnh nhân sốt xuất huyết dengue nặng=Study on the manifestation and discriminant validity of some clinical and sub-clinical features between surviving and death groups in patients with severe dengue fever

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Tác giả: Tuấn Anh Đỗ, Văn Tổng Hoàng, Văn Nam Lê, Minh Nam Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y dược lâm sàng 108, 2024

Mô tả vật lý: tr.40-46

Bộ sưu tập: Báo, Tạp chí

ID: 244872

Thêm vào giỏ

To determine the manifestations and discriminant validity of some clinical and laboratory test features between survival and death groups in patients with severe dengue hemorrhagic fever. Subject and method: Using comparative description and ROC curve to determine discriminant validity of some clinical and laboratory test features in 68 patients with severe dengue fever at Military Hospital 103. Result: The proportion of patients with underlying diseases, symptoms of consciousness disorder, and shock in the survival group were 34%, 4%, 16%, and that in the death group were 77.8%, 33.3%, 61.1% respectively. The number of white blood cells, neutrophils, creatinine, APTT time, CRP in the death group were higher than that in the survival group. Red blood cell counts, hemoglobin, hematocrit and prothrombin ratio in the death group were lower than that in the survival group. The AUC values of age, white blood cell count, neutrophil count, creatinine, APTT, red blood cell count, hemoglobin, hematocrit and prothrombin ratio to distinguish between the survival and death groups range from 0.7 to 0.8 with p<
0.05
Conclusion: The death group had a higher rate of underlying disease, shock, consciousness disorder than that in the survival group. Age, white blood cell count, neutrophil count, creatinine, APTT, red blood cell count, hemoglobin, hematocrit can be used to distinguish between survival and death groups in patients with severe dengue fever (p<
0,05).Xác định biểu hiện và giá trị phân biệt của một số đặc điểm lâm sàng, xét nghiệm giữa nhóm sống - tử vong ở bệnh nhân sốt xuất huyết Dengue nặng. Đối tượng và phương pháp: Mô tả có so sánh, sử dụng đường cong ROC xác định giá trị phân biệt ở 68 bệnh nhân sốt xuất huyết Dengue nặng tại Bệnh viện Quân y 103. Kết quả: Tỷ lệ bệnh nhân có bệnh lý nền, triệu chứng rối loạn ý thức, sốc ở nhóm sống lần lượt là 34%, 4%, 16%
ở nhóm tử vong 77,8%, 33,3%, 61,1%. Số lượng bạch cầu, bạch cầu neutrophil, creatinin, thời gian APTT, CRP ở nhóm tử vong cao hơn nhóm sống. Xét nghiệm hồng cầu, huyết sắc tố, hematocrit, tỷ lệ prothrombin ở nhóm tử vong thấp hơn nhóm sống. Diện tích dưới đường cong (AUC) của các chỉ số tuổi, số lượng bạch cầu, bạch cầu neutrophil, creatinin, thời gian APTT, hồng cầu, huyết sắc tố, hematocrit, tỷ lệ prothrombin để phân biệt giữa 2 nhóm sống và tử vong dao động từ 0,7 đến 0,8 với p<
0,05. Kết luận: Bệnh nhân nhóm tử vong có tỷ lệ có bệnh lý nền, rối loạn ý thức, sốc cao hơn bệnh nhân ở nhóm sống. Các chỉ số tuổi, số lượng bạch cầu, số lượng neutrophil, creatinin, thời gian APTT, hồng cầu, huyết sắc tố, hematocrit, tỷ lệ prothrombin có giá trị phân biệt khá tốt giữa 2 nhóm sống và tử vong ở bệnh nhân sốt xuất huyết Dengue nặng (với p<
0,05).

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