Nghiên cứu thời gian và đánh giá kết quả điều trị tái thông bằng phương pháp tiêu sợi huyết ở bệnh nhân đột quỵ nhồi máu não cấp tại Bệnh viện Đa khoa Trung ương Cần Thơ từ năm 2022 đến năm 2024=Research on the timing and outcomes of revascularization using thrombolysis method in acute ischemic stroke patients at Can Tho central general hospital from 2022 to 2024

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Tác giả: Thị Minh Đức Nguyễn, Anh Thư Trần

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y dược học Cần Thơ, 2024

Mô tả vật lý: tr.189-195

Bộ sưu tập: Báo, Tạp chí

ID: 245056

Thêm vào giỏ

Đột quỵ nhồi máu não cấp là nguyên nhân gây tử vong hàng đầu. Chiến lược điều trị tiêu sợi huyết qua nhiều nghiên cứu cho thấy giảm tỷ lệ tử vong nhưng không đồng nhất do tác động từ nhiều yếu tố. Mục tiêu nghiên cứu: 1). Xác định thời gian điều trị tái thông ở bệnh nhân đột quỵ nhồi máu não cấp tại Bệnh viện Đa khoa Trung ương Cần Thơ từ 2022 đến 2024
2). Đánh giá kết quả điều trị tái thông và các yếu tố ảnh hưởng ở bệnh nhân đột quỵ nhồi máu não cấp tại Bệnh viện Đa khoa Trung ương Cần Thơ từ 2022 đến 2024. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên 43 bệnh nhân được chẩn đoán nhồi máu não và điều trị tái thông bằng tiêu sợi huyết đường tĩnh mạch tại Khoa Đột quỵ - Bệnh viện Đa khoa Trung ương Cần Thơ năm 2022 – 2024. Kết quả: Đa số bệnh nhân ≥ 65 tuổi, nam chiếm 67,4%. Tiền sử bệnh tăng huyết áp chiếm 86,1%. Đánh giá kết quả chung: tốt chiếm tỷ lệ cao nhất 41,9%, trung bình và kém lần lượt là 34,9% và 23,3%. Nhóm đối tượng có tiền sử tăng huyết áp có kết quả tốt ưu thế hơn so với nhóm không có tiền sử tăng huyết áp (45,9% và 16,7%) (p =0,028). Đối tượng chọn xe cấp cứu có kết cục tốt – trung bình (90,9%) cao hơn so với chọn xe nhà (76,7%) và xe công cộng (0%), khác biệt có ý nghĩa thống kê (p = 0,03). Kết luận: Trung bình thời gian khởi phát – nhập viện 165,09 ± 50,14, nhập viện – thăm khám 24,21 ± 24,76, cửa – kim 62,26 ± 52,17, khởi phát – điều trị 227,35 ± 68,50. Kết cục tốt sau điều trị chiếm tỷ lệ cao 41,9%. Phương tiện vận chuyển và tăng huyết áp là hai yếu tố ảnh hưởng đến kết quả điều trị chung.In Vietnam, acute ischemic stroke is a leading cause of death. The treatment strategy of thrombolytic therapy has shown variable results due to the influence of multiple factors. Objectives: 1). To determine the reperfusion treatment time in patients with acute ischemic stroke at Can Tho Central General Hospital from 2022 to 2024
2). To evaluate the reperfusion treatment outcomes and influencing factors in patients with acute ischemic stroke at Can Tho Central General Hospital from 2022 to 2024. Materials and methods: A cross-sectional descriptive study of 43 patients diagnosed with ischemic stroke and treated with intravenous thrombolytic therapy at the Stroke Department Can Tho Central General Hospital from 2022 to 2024. Results: The majority of patients were aged ≥ 65 years, with males accounting for 67.4%. A history of hypertension was present in 86.1% of cases. General outcome assessment: a good outcome was the highest proportion at 41.9%, followed by moderate and poor outcomes at 34.9% and 23.3%, respectively. The group with a history of hypertension had a better outcome compared to the group without a history of hypertension (45.9% and 16.7%) (p=0.028). Patients who chose ambulance transport had better outcomes (90.9%) compared to those who chose private vehicles (76.7%) and public transportation (0%), with statistically significant differences (p = 0.03). Conclusions: The average time from onset to hospital admission was 165.09 ± 50.14, admission to evaluation 24.21 ± 24.76, door-to-needle time 62.26 ± 52.17, and onset-to-treatment time 227.35 ± 68.50. A good treatment outcome was the most common 41.9%. Mode of transportation and hypertension were two factors influencing the overall treatment outcome.

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