Đặc điểm lâm sàng, sự nảy chồi u và mô bệnh học của ung thư biểu mô đại - trực tràng tại Bệnh viện Ung Bướu Cần Thơ và Bệnh viện Đại học Y Dược Cần Thơ năm 2022 - 2023=Clinical, tumor budding and histologic characteristics of colorectal carcinoma in can tho oncology hospital and Can Tho university of medicine and pharmacy hospital in 2022-2023

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Tác giả: Thảo Nhi Bùi, Đạt Minh Đỗ, Thị Kim Thoa Lâm, Như Bình Nguyễn, Phúc Duy Nguyễn, Hiện Đình Nghi Phạm

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y dược học Cần Thơ, 2024

Mô tả vật lý: tr.89-95

Bộ sưu tập: Metadata

ID: 245136

Thêm vào giỏ

Mô tả một số đặc điểm lâm sàng liên quan, sự nảy chồi u, đặc điểm mô bệnh học của ung thư biểu mô đại trực tràng. Tìm hiểu mối tương quan giữa đặc điểm nảy chồi u với một số đặc điểm lâm sàng, mô bệnh học của ung thư biểu mô đại - trực tràng. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên 88 bệnh nhân được chẩn đoán ung thư biểu mô đại trực tràng tại Bệnh viện Ung bướu Cần Thơ và Khoa Ung bướu - Bệnh viện Trường Đại học Y Dược Cần Thơ năm 2022-2023. Kết quả: Trong 88 đối tượng nghiên cứu ghi nhận nhóm tuổi phổ biến nhất là từ 60-69, nam giới chiếm đa số (65,9%). Vị trí u gặp nhiều nhất là ở trực tràng (36,4%) và đại tràng xích ma (34,1%). Ung thư biểu mô tuyến thông thường chiếm đa số (78,4%) và thể sùi là phổ biến nhất (53,4%). Độ biệt hóa vừa và kém chiếm đa số với tỷ lệ lần lượt là 73,9% và 23,9%. Mật độ xâm lấn trên vi thể đến dưới thanh mạc hoặc mô xung quanh đạitrực tràng (pT3) chiếm tỷ lệ nhiều nhất (39,8%). Mức độ nảy chồi u liên quan có ý nghĩa thống kê với độ biệt hóa trong ung thư đại trực tràng (p <
0,001). Kết luận: Ung thư biểu mô tuyến thông thường là chiếm tỷ lệ cao nhất với 78,4%. Đa số là biệt hóa vừa và kém chiếm với tỷ lệ lần lượt là 73,9% và 23,9%.To describe some related clinical features, tumor budding, histopathological characteristics of colorectal carcinoma. To determine the relationship between tumor budding characteristics and some related clinical and histopathological features of colorectal carcinoma. Materials and methods: A cross-sectional descriptive study on 88 patients diagnosed with colorectal carcinoma at Can Tho Oncology Hospital and Oncology Department - Can Tho University of Medicine and Pharmacy Hospital in 2022-2023. Results: Among the 88 patients, the most common age group was from 60-69, men accounted for the majority (65.9%). The most common tumor locations were in the rectum (36.4%) and the sigmoid colon (34.1%). Adenocarcinoma accounted for the majority (78.4%) and protuberant subtype was the most common (53.4%). Moderately and poorly differentiated accounted for the majority with 73.9% and 23.9% respectively. The density of microscopic invasion to subserosal or surrounding colorectal tissue (pT3) accounted for the highest rate (39.8%). Tumor budding is statistically significantly related to differentiation in colorectal cancer (p<
0.001). Conclusions: Adenocarcinoma is usually the highest rate with 78.4%. Most of them were moderately and poorly differentiated, accounting for 73.9% and 23.9%, respectively.

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