Đánh giá mức độ nặng và phân tích kết cục điều trị ở bệnh nhân viêm phổi cộng đồng qua một số thang điểm tại Bệnh viện Đa khoa Trung Ương Cần Thơ năm 2022-2023=Evaluate severity and analysis for treatment outcome in patients with community-acquired pneumonia of some scores at Can Tho central general hospital in 2022-2023

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Thị Mỹ Thuý Cao, Lê Hoàng Nguyên Trịnh

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y dược học Cần Thơ, 2024

Mô tả vật lý: tr.110-117

Bộ sưu tập: Metadata

ID: 245143

Thêm vào giỏ

Community-acquired pneumonia (CAP) is one of the acute lower respiratory tract infections with high morbidity and mortality. Early diagnosis and appropriate severity assessment help to select antibiotics treatment, and help to improve patient mortality. Objectives: To evaluate severity and relationship with treatment outcome in patients with community-acquired pneumonia through the CRB-65, CURB-65, ECURB-65 and PSI scores. Materials and methods: Cross-sectional, prospective descriptive study. To select a convenient sample of 91 patients diagnosed with CAP from October 2022 to October 2023. Results: The rates of CAP in the CRB- 65≥2, CURB-65≥3, ECURB-65≥5, and PSI≥IV group were 12.1%
6.6%
10.9%
52.7% with p<
0.01. The rates of treatment failure outcomes in the CRB-65≥2, CURB-65≥3, ECURB-65≥5, and PSI≥IV groups were 45.4%
50%
40%
12.5% with p<
0.05. The area under the curve in prediction of treatment failure through the CRB-65, CURB-65, ECURB-65, and PSI scores were 0.905 (p<
0.01)
0.894 (p=0.01)
0.927 (p<
0.01) and 0.909 (p=0.01). Conclusions: The ECURB-65 score has good support for predicting treatment outcomes in hospitalized CAP patients with an AUC of 0.927. In addition, the CRB-65 score which is easy-to-remember also helps to predict clinical treatment outcomes with an AUC of 0.905.Viêm phổi cộng đồng là một trong các bệnh lý nhiễm trùng đường hô hấp dưới cấp tính thường gặp có tỷ lệ tử vong cao. Chẩn đoán sớm và đánh giá đúng mức độ nặng giúp thầy thuốc lựa chọn kháng sinh kinh nghiệm hợp lý nhằm cải thiện kết cục điều trị và tử vong ở bệnh nhân. Mục tiêu nghiên cứu: Đánh giá mức độ nặng và mối liên quan với kết cục điều trị ở bệnh nhân viêm phổi cộng đồng qua các thang điểm CRB-65, CURB-65, ECURB-65, PSI. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang, tiến cứu. Chọn mẫu thuận tiện gồm 91 bệnh nhân chẩn đoán viêm phổi cộng đồng từ tháng 10/2022 đến tháng 10/2023. Kết quả: Tỷ lệ bệnh nhân viêm phổi cộng đồng trong các nhóm CRB-65≥2, CURB-65≥3, ECURB-65≥5 và PSI≥IV lần lượt là 12,1%
6,6%
10,9%
52,7% với p<
0,01. Tỷ lệ kết cục điều trị thất bại trong các nhóm CRB-65≥2, CURB-65≥3, ECURB-65≥5và PSI≥IV lần lượt là 45,4%
50%
40%
12,5% với p<
0,05. Diện tích dưới đường cong trong tiên đoán kết cục điều trị thất bại qua các thang điểm CRB-65, CURB-65, ECURB-65, PSI lần lượt là 0,905 (p<
0,01)
0,894 (p<
0,01)
0,927 (p<
0,01) và 0,909 (p=0,01). Kết luận: Thang điểm ECURB-65 có khả năng hỗ trợ tốt dự đoán kết cục điều trị ở bệnh nhân VPCĐ nhập viện với AUC là 0,927. Ngoài ra, thang điểm CRB65 với tính đơn giản, dễ nhớ cũng giúp tiên đoán kết cục điều trị trên lâm sàng với AUC là 0,905.

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