Đặc điểm phân loại lớp Ambler carbapenemase trên Acinetobacter spp. tại Bệnh viện Nhi Đồng 2=Characteristics of classification of Ambler carbapenemase on Acinetobacter spp. at Children's Hospital 2

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Tác giả: Thế Trung Bùi, Minh Nga Cao, Thị Giao Tiên Huỳnh, Thị Thanh Thùy Lê, Thị Thắm Nguyễn, Thị Thùy Trang Nguyễn

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.127-133

Bộ sưu tập: Báo, Tạp chí

ID: 246270

Thêm vào giỏ

Nghiên cứu này nhằm xác định tỷ lệ sinh men carbapenemase và tỷ lệ phân bố các lớp Ambler carbapenemase ở Acinetobacter spp.. Phương pháp nghiên cứu: Nghiên cứu cắt ngang mô tả, được thực hiện trên 93 chủng Acinetobacter spp. tại Bệnh viện Nhi Đồng 2 trong khoảng thời gian từ 01/2019 – 12/2020. Kết quả: Tỷ lệ Acinetobacter spp. sinh men carbapenemase chiếm 82,8% (77/93) cao hơn so với 17,2% (16/93) của vi khuẩn không sinh men carbapenemase. Tỷ lệ Acinetobacter spp. sinh men carbapenemase lớp Ambler D cao nhất chiếm 39,8% (37/93), tiếp theo là lớp Ambler B với 32,2% (30/93), âm tính 17,2% (16/93) và cuối cùng có 10,8% (10/93) chủng có sinh men carbapenemase nhưng không xác định được lớp Ambler. Kết luận: Không có mối liên quan giữa Acinetobacter spp. sinh men carbapenemase ở các lớp Ambler khác nhau với giới tính, tuổi, loại bệnh phẩm, khoa, chẩn đoán và số ngày nằm viện. Có sự khác biệt có ý nghĩa thống kê giữa Acinetobacter spp. sinh men carbapenemase ở các lớp Ambler khác nhau với tình trạng bệnh nhân khi xuất viện.This study conducted a descriptive cross-sectional investigation on 93 strains of Acinetobacter spp. at Children's Hospital 2 from January 2019 to December 2020, with the goal of evaluating the rate of carbapenemase production and the distribution rate of Ambler carbapenemase classes in Acinetobacter spp. Results: Acinetobacter spp. bacteria that produce carbapenemase enzymes account for 82.8% (77/93), compared to 17.2% (16/93) of bacteria that do not. The Ambler D class of Acinetobacter spp. produces the highest carbapenemase, accounting for 39.8% (37/93), followed by the Ambler B class with 32.2% (30/93), the negative 17.2% (16/93), and lastly 10.8% (10/93). However, the Ambler class has yet to be found. Conclusions: There was no correlation between Acinetobacter spp. carbapenemase production and sex, age, specimen type, department, diagnosis, or number of days in the hospital across Ambler classes. The generation of carbapenemase by Ambler class Acinetobacter spp. differs significantly from the patient's condition upon discharge.

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