Cation Channel TMEM63A Autonomously Facilitates Oligodendrocyte Differentiation at an Early Stage.

• Tác giả: Guiquan Chen, Gui-Fang Duan, Fei Li, Yun Stone Shi, Xiao-Yu Teng, He Wang, Yue-Ying Wang, Dan Wu, Rong Xu, Yun Xu, Jian-Jun Yang, Yongguo Yu, Yan-Yu Zang, Yongkun Zhan, Linlin Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 641.5784 Cooking
• Thông tin xuất bản: Singapore : Neuroscience bulletin , 2025
• Bộ sưu tập: NCBI
• ID: 248081

Tóm tắt

 Accurate timing of myelination is crucial for the proper functioning of the central nervous system. Here, we identified a de novo heterozygous mutation in TMEM63A (c.1894G>
 A
  p. Ala632Thr) in a 7-year-old boy exhibiting hypomyelination. A Ca