ANTI-MICROBIAL ACTIVITY OF SOME Pt(II) COMPLEXES BEARING 8-OXYQUINOLINE (8-OQ) AND EUGENOL DERIVATIVE AND 3D-STRUCTURE OF COMPLEX [PtCl(8-OQ)(EUGENOL)]=ANTI-MICROBIAL ACTIVITY OF SOME Pt(II) COMPLEXES BEARING 8-OXYQUINOLINE (8-OQ) AND EUGENOL DERIVATIVE AND 3D-STRUCTURE OF COMPLEX [PtCl(8-OQ)(EUGENOL)]

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Tác giả: Dang Xuan Nhat Sang, Manh Hieu Duong, Hoang Ninh Nguyen, Thi Thanh Chi Nguyen

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Khoa học - Trường Đại học Sư phạm Hà Nội: Khoa học Tự nhiên, 2024

Mô tả vật lý: tr.118

Bộ sưu tập: Metadata

ID: 248311

 Four complexes including [PtCl(8-OQ)](arylolefin)] (arylolefin: Eug, M1
 Aceug, M2, Eteug, M3, Preug, M4) were obtained by the reaction between8-hydroxyquinoline and K[PtCl3(arylolefin)] in high yields. The 3D structure of M1has been determined for the first time by DFT calculation combined with theexperimental NOESY spectrum. The result showed that M1 exists as distortedsquare-planar coordination with angles of O-Pt-Cl and N-Pt-O of 176.4o and 81.0orespectively. In which 8-OQ coordinates with Pt(II) through both the N and O atoms,Eug bonds with Pt(II) via the C=Cally and in trans position to the N atom of 8-OQ.The investigation of the biological activities of the synthesized complexes showedthat they display weak anti-bacterial and antifungal activities.Four complexes including [PtCl(8-OQ)](arylolefin)] (arylolefin: Eug, M1
 Aceug, M2, Eteug, M3, Preug, M4) were obtained by the reaction between8-hydroxyquinoline and K[PtCl3(arylolefin)] in high yields. The 3D structure of M1has been determined for the first time by DFT calculation combined with theexperimental NOESY spectrum. The result showed that M1 exists as distortedsquare-planar coordination with angles of O-Pt-Cl and N-Pt-O of 176.4o and 81.0orespectively. In which 8-OQ coordinates with Pt(II) through both the N and O atoms,Eug bonds with Pt(II) via the C=Cally and in trans position to the N atom of 8-OQ.The investigation of the biological activities of the synthesized complexes showedthat they display weak anti-bacterial and antifungal activities.
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