Mitochondrial Transport Proteins

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Tác giả: Ferdinando Palmieri

Ngôn ngữ: eng

ISBN-13: 978-3036534091

Ký hiệu phân loại:

Thông tin xuất bản: Basel : MDPI - Multidisciplinary Digital Publishing Institute, 2022

Mô tả vật lý: 1 electronic resource (476 p.)

Bộ sưu tập: Tài liệu truy cập mở

ID: 249570

Mitochondrial transporters are membrane-inserted proteins which provide a link between metabolic reactions occurring within the mitochondrial matrix and outside the organelles by catalyzing the translocation of numerous solutes across the mitochondrial membrane. They include the mitochondrial carrier family members, the proteins involved in pyruvate transport, ABC transporters and channels, and are, therefore, essential for many biological processes and cell homeostasis. Identification and functional studies of many mitochondrial transporters have been performed over the years using both in vitro and in vivo systems. The few recently solved structures of these transporters have paved the way for further investigations. Furthermore, alterations in their function are responsible for several diseases.
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