Prognostic value of transient ischemic dilation on Rubidium-82 positron emission tomography myocardial perfusion imaging.

• Tác giả: Vikram Agarwal, Timothy M Bateman, Phillip Lim, A Iain McGhie, Krishna K Patel, Poghni A Peri-Okonny, Basera Sabharwal, Leslee J Shaw, Annapoorna Singh
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology , 2025
• Bộ sưu tập: NCBI
• ID: 252013

Tóm tắt

 BACKGROUND: Transient ischemic dilation (TID) of the left ventricular (LV) cavity is considered a high-risk marker in patients with abnormal single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). Stress image acquisition with rubidium-82 ( METHODS: A total of 9878 consecutive patients with LVEF ≥40% undergoing rest/pharmacologic stress RESULTS: The mean age of the cohort was 69.0 (11.7) years with 56.1% being female, 49.8% having known CAD, and 27.9% having abnormal perfusion (SSS>
 0). There were 451 cardiac deaths. Higher TID ratios were associated with higher risk of cardiac death, even after accounting for LVEF-R and MBFR (HR per .1 unit increase = 1.25 (1.11, 1.41), P <
  .001). This was seen in patients with both normal (HR for TID per .1 unit increase = 1.24 (95% CI: 1.01, 1.52), P = .04) and abnormal perfusion (HR for TID per .1 unit increase = 1.14 (95% CI: 1.02, 1.28), P = .03). CONCLUSIONS: TID on rest/stress