Seventh ISNS Reference Preparation for Neonatal Screening for Thyroid Stimulating Hormone, Phenylalanine, and 17α-Hydroxyprogesterone in Blood Spots.

• Tác giả: James R Bonham, J Gerard Loeber, Peter C J I Schielen, Dianne Webster
• Ngôn ngữ: eng
• Ký hiệu phân loại: 286.732 Seventh-Day Adventist Church
• Thông tin xuất bản: Switzerland : International journal of neonatal screening , 2025
• Bộ sưu tập: NCBI
• ID: 252063

Tóm tắt

The International Society for Neonatal Screening (ISNS) has supported the standardization of the measurement of key biochemical markers for the neonatal screening of diseases: thyroid-stimulating hormone (TSH) for congenital hypothyroidism, phenylalanine (PHE) for phenylketonuria, and 17α-hydroxyprogesterone (17OHP) for congenital adrenal hyperplasia. These diseases are commonly a part of neonatal screening panels worldwide. The ISNS provides a series of secondary reference materials to the manufacturers of neonatal screening reagents to assist in the production of calibration materials for kits. This technical note describes the manufacture of the seventh combined dried blood spot reference preparation for neonatal screening (RPNS) for these analytes.