Kết quả điều trị bệnh nhân viêm đầu dài gân nhị đầu bằng liệu pháp tiêm corticoid tại chỗ kết hợp với uống Diacerein tại Bệnh viện Trung ương Thái Nguyên=Effectiveness of corticoid injection theraphy combined with oral Diacerein in paitients with long head biceps tendinitis

0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Thị Minh Hằng Hoàng, Thị Bình Lưu

Ngôn ngữ: vie

Ký hiệu phân loại:

Thông tin xuất bản: Tạp chí Y học Việt Nam (Tổng hội Y học Việt Nam), 2024

Mô tả vật lý: tr.280-284

Bộ sưu tập: Báo, Tạp chí

ID: 252464

Thêm vào giỏ

Đánh giá kết quả điều trị viêm đầu dài gân nhị đầu sau tiêm corticoid tại chỗ kết hợp với uống Diacerein 3 tháng ở các bệnh nhân điều trị tại khoa Cơ xương khớp bệnh viện Trung Ương Thái Nguyên. Đối tượng và phương pháp nghiên cứu: nghiên cứu can thiệp trên 72 bệnh nhân viêm đầu dài gân nhị đầu được tiêm corticoid tại chỗ, sau đó chia thành 2 nhóm: nhóm nghiên cứu 36 bệnh nhân uống Diacerein 3 tháng, nhóm chứng 36 bệnh nhân uống Glucosamin sulfat 3 tháng. Kết quả: Sau can thiệp 3 tháng có sự cải thiện rõ rệt về lâm sàng và hình ảnh siêu âm ở cả hai nhóm: lâm sàng VAS trung bình giảm từ 6.39±0.87 xuống 1,53±0,91 ở nhóm nghiên cứu và từ 6,78±0,96 xuống 2,00±1,09 ở nhóm chứng, SPADI trung bình giảm từ 59,92±6,05 xuống 24,14±3,63 ở nhóm nghiên cứu và từ 62,53±5,40 xuống 26,33±3,82 ở nhóm chứng, góc vận động khớp vai trung bình tăng từ 129,72±11,33 lên 167,78±8,98 với nhóm nghiên cứu và từ 121,94±10,09 lên 163,33±7,93 với nhóm chứng
63,9% nhóm nghiên cứu và 55,6% nhóm chứng có hình ảnh siêu âm trở về bình thường sau 3 tháng can thiệp. Ở nhóm dùng diacerein có tỷ gặp các dụng phụ nhiều hơn đáng kể so với nhóm chứng, hay gặp nhất là đại tiện phân lỏng (p<
0,05). Kết luận: Liệu pháp tiêm corticoid tại chỗ kết hợp với uống diacerein hoặc glucosamin sulfat 3 tháng đã cải thiện đáng kể về lâm sàng và hình ảnh siêu âm gân nhị đầu, tuy nhiên tác dụng phụ ở nhóm dùng diacerein nhiều hơn đáng kể so với nhóm glucosamin sulfat.Evaluating the results of long head biceps tendinitis treatment by local corticoid injection combined with oral Diacerein for 3 months in patients treated at the Rheumatology Department, Thai Nguyen National Hospital. Subjects and methods: Interventional study, 72 long head biceps tendinitis patients locally injected corticoid are divided into two groups: experimental group contains 36 patients received oral diacerein for 3 months and control group contains 36 patients received oral glucosamin sulfat for 3 months. Result: after 3 months of the treatment, there was an improvement in clinical symtoms and ultrasound images in both groups: clinical symtoms the average VAS decreased from 6.39±0.87 to 1.53±0.91 in the experimental group and from 6.78±0.96 to 2.00±1.09 in the control group, the average SPADI decreased from 59.92±6.05 to 24.14±3.63 in the experimental group and from 62.53±5.40 to 26.33±3.82 in the control group, the average shoulder range of movement increased from 129.72±11.33 to 167.78±8.98 in the experimental group and from 121.94±10.09 to 163.33±7.93 in the control group. 63.9% of the experimental group and 55.6% of the control group had normal ultrasound images after 3 months of the treatment. In the group using diacerein, the incidence of side effects was significantly higher than in the control group, the most common being loose stools (p<
0,05). Conclusion: Local corticoid injection therapy combined with oral diacerein or glucosamine sulfate for 3 months significantly improved clinical and ultrasound images of the biceps tendon, however side effects in the diacerein group were significantly more than in the glucosamine sulfate group.

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