The interactive toxic effect of homocysteine and copper on cardiac microvascular endothelial cells during ischemia-reperfusion injury.

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Tác giả: Shansong Gao, Tianxiang Huang, Songqing Lai, Haipeng Liu, Xiaoming Liu, Chengpeng Qiu, Ning Wang, Wan Zhang

Ngôn ngữ: eng

Ký hiệu phân loại: 363.737 Measures to prevent, protect against, limit effects of pollution

Thông tin xuất bản: Ireland : Chemico-biological interactions , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 254152

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Hyperhomocysteinemia (HHcy) is associated with the development and progression of chronic cardiovascular diseases through the deleterious effects of high levels of homocysteine (Hcy) on the cardiovascular system. However, the exact mechanism of action of Hcy on the acute injury of the cardiovascular system following ischemia/reperfusion (I/R) remains unclear. The present study demonstrated that copper mobilization occurs during cardiac I/R, and the interactive toxic effect of Hcy and mobile Cu

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