Myricetin has a significant role in pharmacology, specifically in traditional Chinese medicine. The most intriguing pharmacological action of myricetin consists of its multi-pathway anticancer effects. Therefore, rapid and selective isolation of myricetin from garlic and apple juices has notable pharmacological benefits. Chitosan-graphene oxide-based biomacroporous cryogel are highly efficient and environmentally friendly materials for adsorption. The current study involved the synthesis of chitosan-graphene oxide-based biomacroporous cryogel sorbent for the selective recovery of myricetin. The characterization investigation utilizing SEM, XRD, EDS and FTIR demonstrated the successful synthesis of a chitosan-graphene oxide-based biomacroporous cryogel. Additionally, XPS effectively revealed the interaction of functional groups on the biomacroporous cryogel sorbent with myricetin. The maximum adsorption capacity for myricetin, under optimized conditions, was 167 mg g