The research we present in this article focuses on a 9-m CX-100 wind turbine blade, designed by a team led by Sandia National Laboratories and manufactured by TPI Composites Inc. The key difference between the 9-m blade and baseline CX-100 blades is that this blade contains fabric wave defects of controlled geometry inserted at specified locations along the blade length. The defect blade was tested at the National Wind Technology Center at the National Renewable Energy Laboratory using a schedule of cycles at increasing load level until failure was detected. Our researchers used digital image correlation, shearography, acoustic emission, fiber-optic strain sensing, thermal imaging, and piezoelectric sensing as structural health monitoring techniques. Furthermore, this article provides a comparison of the sensing results of these different structural health monitoring approaches to detect the defects and track the resultant damage from the initial fatigue cycle to final failure.